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com menor incid&#234;ncia&#44; apresenta les&#245;es nas &#225;reas de contato&#44; que podem se disseminar&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">O diagn&#243;stico envolve hist&#243;ria ocupacional&#44; sincronia entre o in&#237;cio do quadro e o per&#237;odo de exposi&#231;&#227;o&#44; correla&#231;&#227;o entre localiza&#231;&#227;o das les&#245;es e contato&#44; melhoria com o afastamento e piora com retorno ao trabalho e teste de contato&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1&#8211;3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Neste estudo&#44; foram analisados&#58; a frequ&#234;ncia de DCO em pacientes submetidos aos testes de contato em ambulat&#243;rio n&#227;o especializado em DOs&#44; entre 2004 e 2017&#59; a distribui&#231;&#227;o por idade&#44; g&#234;nero&#44; atividade profissional e localiza&#231;&#227;o da dermatose&#59; 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No entanto&#44; a DCI &#233; o subtipo mais comum em todo o mundo&#44; especialmente em casos ocupacionais&#44; com frequ&#234;ncia estatisticamente maior neste grupo &#40;p &#60; 0&#44;001&#41;&#46; A propor&#231;&#227;o desses diagn&#243;sticos varia de acordo com a regi&#227;o&#44; por diferen&#231;as em tipos de ind&#250;stria&#44; normas de regulamenta&#231;&#227;o&#44; sistemas de notifica&#231;&#227;o e disponibilidade de centros capacitados para testes de contato&#46; J&#225; a DA pode ser considerada DO&#44; uma vez que muitos trabalhadores pioram ap&#243;s contato com os al&#233;rgenos e irritantes do ambiente de trabalho&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Entre as DCOs&#44; a m&#233;dia das idades foi de 42&#44;1 anos&#44; enquanto nas DCNOs foi de 47&#44;5 anos &#40;p &#60; 0&#44;005&#41;&#44; gerando perdas aos sistemas produtivos e seguridade social&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Entre as DCOs havia 182 &#40;52&#44;1&#37;&#41; mulheres e 167 &#40;47&#44;9&#37;&#41; homens&#44; enquanto na DCNO eram 797 &#40;77&#44;3&#37;&#41; mulheres e 234 &#40;22&#44;7&#37;&#41; homens&#46; A frequ&#234;ncia de mulheres foi maior entre as DCNOs &#40;p &#60; 0&#44;005&#41;&#44; pois provavelmente representam a parcela da popula&#231;&#227;o que mais procura atendimento m&#233;dico&#44; mas significantemente menor no grupo ocupacional&#44; talvez pelo fato de haver mais trabalhadores homens nas atividades com exposi&#231;&#227;o a sensibilizantes e irritantes&#46; Al&#233;m disso&#44; as mulheres tendem a ser mais adeptas ao uso de equipamentos de prote&#231;&#227;o individual e cuidados preventivos&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">6</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">As profiss&#245;es mais prevalentes na DCO est&#227;o na <a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#44; e envolvem os profissionais com atividades &#250;midas &#40;contato com &#225;gua &#62; 2 horas di&#225;rias&#44; ou lavagens das m&#227;os &#62; 20 vezes no dia&#41; ou exposi&#231;&#227;o a conhecidos sensibilizantes e irritantes&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">7</span></a></p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0060" class="elsevierStylePara elsevierViewall">O tempo de evolu&#231;&#227;o da doen&#231;a na DCO foi de 29&#44;2 meses&#44; enquanto na DCNO foi de 39&#44;5 meses &#40;p &#60; 0&#44;005&#41;&#46; A dificuldade em manter as atividades laborais talvez tenha favorecido a busca por aux&#237;lio de maneira mais precoce nos casos de DCO&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Quanto &#224; localiza&#231;&#227;o da dermatose&#44; houve diferen&#231;a estat&#237;stica em rela&#231;&#227;o a DCO para m&#227;os &#40;regi&#245;es palmar e dorso&#41; e antebra&#231;os &#40;p &#60; 0&#44;001&#41;&#44; enquanto em portadores de DCNO a face foi a mais acometida &#40;582&#47;66&#44;7&#37;&#41;&#46; Essa diferen&#231;a &#233; esperada&#44; j&#225; que as DCOs acometem principalmente as m&#227;os&#44; que manipulam diretamente produtos irritantes ou sensibilizantes&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Os principais sensibilizantes relevantes observados nos dois grupos est&#227;o no <a class="elsevierStyleCrossRef" href="#tbl0010">tabela 2</a>&#59; o n&#237;quel &#233; o mais importante&#44; presente em atividades ocupacionais ou n&#227;o&#46; As m&#227;os s&#227;o acometidas em raz&#227;o do contato com ferramentas de trabalho&#44; como agulhas de costura&#44; pin&#231;as&#44; alicates de cut&#237;culas&#44; chaves e tesouras&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">O bicromato de pot&#225;ssio est&#225; relacionado aos pedreiros&#44; por sua presen&#231;a no cimento &#40;como contaminante&#44; resultante do processo de fabrica&#231;&#227;o&#41;&#44; e &#233; um importante al&#233;rgeno ocupacional em estudos semelhantes&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">8</span></a></p><p id="par0080" class="elsevierStylePara elsevierViewall">Os grupos tiuram&#44; carba e MBT s&#227;o agentes vulcanizadores da borracha&#44; comuns nas luvas&#44; utilizadas em diversos setores produtivos&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">A resina ep&#243;xi &#233; um material utilizado em diversos produtos como tintas&#44; acabamento para pisos&#44; fibras de vidro&#44; adesivos para metais&#44; madeiras e concreto&#46; Desse modo&#44; as les&#245;es surgem em v&#225;rias localiza&#231;&#245;es&#44; e medidas de prote&#231;&#227;o s&#227;o dif&#237;ceis&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">9</span></a></p><p id="par0090" class="elsevierStylePara elsevierViewall">Quaternium 15 &#40;conservante liberador de formalde&#237;do&#41;&#44; presente em produtos infantis&#44; cosm&#233;ticos&#44; shampoos de uso veterin&#225;rio&#44; materiais para polimento e ceras&#44; &#233; um al&#233;rgeno onipresente&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">10</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">Alguns al&#233;rgenos apresentaram altas frequ&#234;ncias nos dois grupos &#40;sem diferen&#231;a estat&#237;stica&#41;&#44; entre eles o Kathon CG&#58; DCO &#40;24&#47;6&#44;9&#37;&#41; e DCNO &#40;84&#47;8&#44;2&#37;&#41;&#44; mistura de conservantes de produtos aquosos como cosm&#233;ticos&#44; artigos de limpeza &#40;detergentes&#44; sab&#245;es&#44; &#243;leos lubrificantes&#41; e tintas&#44; tendo os casos ocupacionais ocorrido em trabalhadores de limpeza&#44; cabeleireiros e pintores&#59; e parafenilenodiamina&#44; corante das tinturas de cabelo&#58; DCO &#40;27&#47;7&#44;8&#37;&#41; e DCNO &#40;110&#47;10&#44;7&#37;&#41;&#44; cujos casos ocupacionais ocorreram em cabeleireiros&#44; acometendo as m&#227;os pela n&#227;o utiliza&#231;&#227;o adequada de EPIs&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">No per&#237;odo estudado&#44; a DCO representou 25&#44;3&#37; dos casos submetidos aos testes de contato&#59; o grupo de jovens do sexo masculino &#233; o mais afetado&#44; com impacto para a sa&#250;de do trabalhador e a economia do pa&#237;s&#46; O estudo das DCOs em nosso meio &#233; fundamental para o planejamento de a&#231;&#245;es de preven&#231;&#227;o e capacita&#231;&#227;o diagn&#243;stica dos centros dermatol&#243;gicos&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Suporte financeiro</span><p id="par0105" class="elsevierStylePara elsevierViewall">Nenhum&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Contribui&#231;&#227;o dos autores</span><p id="par0110" class="elsevierStylePara elsevierViewall">Rosana Lazzarini&#58; Concep&#231;&#227;o e planejamento do estudo&#59; elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; obten&#231;&#227;o&#44; an&#225;lise e interpreta&#231;&#227;o dos dados&#59; participa&#231;&#227;o efetiva na orienta&#231;&#227;o da pesquisa&#59; participa&#231;&#227;o intelectual em conduta proped&#234;utica e&#47;ou terap&#234;utica de casos estudados&#59; revis&#227;o cr&#237;tica da literatura&#59; revis&#227;o cr&#237;tica do manuscrito&#59; aprova&#231;&#227;o da vers&#227;o final do manuscrito&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">Mariana de Figueiredo Silva Hafner&#58; Concep&#231;&#227;o e planejamento do estudo&#59; elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; obten&#231;&#227;o&#44; an&#225;lise e interpreta&#231;&#227;o dos dados&#59; participa&#231;&#227;o efetiva na orienta&#231;&#227;o da pesquisa&#59; participa&#231;&#227;o intelectual em conduta proped&#234;utica e&#47;ou terap&#234;utica de casos estudados&#59; revis&#227;o cr&#237;tica da literatura&#59; revis&#227;o cr&#237;tica do manuscrito&#59; aprova&#231;&#227;o da vers&#227;o final do manuscrito&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Nathalie Mie Suzuki&#58; Participa&#231;&#227;o efetiva na orienta&#231;&#227;o da pesquisa&#59; participa&#231;&#227;o intelectual em conduta proped&#234;utica e&#47;ou terap&#234;utica de casos estudados&#59; revis&#227;o cr&#237;tica da literatura&#59; revis&#227;o cr&#237;tica do manuscrito&#59; aprova&#231;&#227;o da vers&#227;o final do manuscrito&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Isabela Marangon Pasotti&#58; Elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; obten&#231;&#227;o&#44; an&#225;lise e interpreta&#231;&#227;o dos dados&#59; aprova&#231;&#227;o da vers&#227;o final do manuscrito&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">Maria Regina de Paula Leite Kraft&#58; Elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; obten&#231;&#227;o&#44; an&#225;lise e interpreta&#231;&#227;o dos dados&#59; aprova&#231;&#227;o da vers&#227;o final do manuscrito&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflito de interesses</span><p id="par0135" class="elsevierStylePara elsevierViewall">Nenhum&#46;</p></span></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Como citar este artigo&#58; Lazzarini R&#44; Hafner MFS&#44; Suzuki NM&#44; Pasotti IM&#44; Kraft MRPL&#46; Occupational contact dermatitis&#58; analysis of cases observed in a service not specialized in occupational dermatosis between 2004 and 2017&#46; An Bras Dermatol&#46; 2022&#59;97&#58;105&#8211;7&#46;</p>"
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Atividade profissional&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Profissionais do lar&#47;limpeza&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">95&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">27&#44;3&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">72&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">20&#44;6&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">26&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">7&#44;4&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">11&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Sulfato de n&#237;quel&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">98&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">28&#44;1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">360&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">p &#61; 0&#44;018&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Bicromato de pot&#225;ssio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">89&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">25&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">87&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">8&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">p &#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Carba mix&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">15&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">51&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">5&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">p &#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Tiuram mix&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">49&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">p &#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Resina ep&#243;xi&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">p &#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Quaternium 15<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">p &#61; 0&#44;021&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MBT mix<span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">p &#61; 0&#44;031&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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        "descripcion" => array:1 [
          "pt" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Principais al&#233;rgenos entre os portadores de DCO comparados aos portadores de DCNO</p>"
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      ]
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      "titulo" => "Refer&#234;ncias"
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        0 => array:2 [
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            0 => array:3 [
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Occupational dermatosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "O&#46; Alchorne Ade"
                            1 => "M&#46;M&#46; Alchorne"
                            2 => "M&#46;M&#46; Silva"
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                    0 => array:2 [
                      "doi" => "10.1590/s0365-05962010000200003"
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                        "tituloSerie" => "An Bras Dermatol&#46;"
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                        "volumen" => "85"
                        "paginaInicial" => "137"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20520928"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Dermatite de contato"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "I&#46; Duarte"
                            1 => "R&#46; Lazzarini"
                            2 => "M&#46; Hafner"
                            3 => "N&#46;A&#46; Monteiro"
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                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "editores" => "W&#46;Belda Junior, N&#46;DiChiachio, P&#46;R&#46;Criado"
                        "titulo" => "Tratado de Dermatologia&#46;"
                        "edicion" => "3 ed&#46;"
                        "serieFecha" => "2018"
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            2 => array:3 [
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The validity of the Mathias criteria for establishing occupational causation and aggravation of contact dermatitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Ingber"
                            1 => "S&#46; Merims"
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                    0 => array:2 [
                      "doi" => "10.1111/j.0105-1873.2004.00273.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Contact Dermatitis&#46;"
                        "fecha" => "2004"
                        "volumen" => "51"
                        "paginaInicial" => "9"
                        "paginaFinal" => "12"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15291825"
                            "web" => "Medline"
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              "identificador" => "bib0065"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Occupational dermatoses reported in Brazil from 2007 to 2014"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;L&#46;Z&#46; Lise"
                            1 => "F&#46;R&#46; Feij&#243;"
                            2 => "M&#46;L&#46;Z&#46; Lise"
                            3 => "C&#46;R&#46;Z&#46; Lise"
                            4 => "L&#46;C&#46;E&#46; Campos"
                          ]
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                    0 => array:2 [
                      "doi" => "10.1590/abd1806-4841.20185314"
                      "Revista" => array:6 [
                        "tituloSerie" => "An Bras Dermatol&#46;"
                        "fecha" => "2018"
                        "volumen" => "93"
                        "paginaInicial" => "27"
                        "paginaFinal" => "32"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29641693"
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              "identificador" => "bib0070"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dermatoses ocupacionais registradas em sistema de notifica&#231;&#227;o na regi&#227;o Sul do Brasil &#40;2007 a 2016&#41;"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "F&#46;M&#46;D&#46; Miranda"
                            1 => "K&#46;S&#46;M&#46; Purim"
                            2 => "L&#46;M&#46;M&#46; Sarquis"
                            3 => "A&#46;N&#46;C&#46; Shwetz"
                            4 => "L&#46;S&#46; Delatorre"
                            5 => "R&#46;M&#46; Saalfeld"
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.5327/Z1679443520180261"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Bras Med Trab&#46;"
                        "fecha" => "2018"
                        "volumen" => "16"
                        "paginaInicial" => "442"
                        "paginaFinal" => "450"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32754659"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Occupational Contact Dermatitis in Spain"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "L&#46; Holgu&#237;n-G&#243;mez"
                            1 => "J&#46; Sastre Dom&#237;nguez"
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                      ]
                    ]
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.18176/jiaci.0131"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Investig Allergol Clin Immunol&#46;"
                        "fecha" => "2017"
                        "volumen" => "27"
                        "paginaInicial" => "134"
                        "paginaFinal" => "136"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28398202"
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Carta ‐ Investigação
Dermatite de contato ocupacional: análise dos casos observados em serviço não especializado em dermatoses ocupacionais entre 2004 e 2017
Rosana Lazzarinia,
Autor para correspondência
rosana.fototerapia@gmail.com

Autor para correspondência.
, Mariana de Figueiredo Silva Hafnera, Nathalie Mie Suzukiaa,b, Isabela Marangon Pasottib, Maria Regina de Paula Leite Kraftb
a Clínica de Dermatologia, Hospital Santa Casa de São Paulo, São Paulo, SP, Brasil
b Escola de Medicina, Santa Casa de São Paulo, São Paulo, SP, Brasil
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Dermatoses ocupacionais &#40;DOs&#41; s&#227;o altera&#231;&#245;es da pele&#44; mucosas e anexos causadas&#44; mantidas ou agravadas por agentes presentes no trabalho&#46; As DOs de maior repercuss&#227;o s&#227;o as dermatites de contato ocupacionais &#40;DCOs&#41;&#44; com impacto no sistema de sa&#250;de&#44; na remunera&#231;&#227;o e na produtividade dos trabalhadores&#46; S&#227;o as principais doen&#231;as ocupacionais no Brasil&#44; embora subdiagnosticadas&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">A dermatite de contato irritativa &#40;DCI&#41; &#233; a forma mais comum&#44; restrita a &#225;reas de contato com irritantes e relacionada &#224; frequ&#234;ncia e dura&#231;&#227;o dessa exposi&#231;&#227;o&#46; A dermatite al&#233;rgica de contato &#40;DAC&#41;&#44; com menor incid&#234;ncia&#44; apresenta les&#245;es nas &#225;reas de contato&#44; que podem se disseminar&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">O diagn&#243;stico envolve hist&#243;ria ocupacional&#44; sincronia entre o in&#237;cio do quadro e o per&#237;odo de exposi&#231;&#227;o&#44; correla&#231;&#227;o entre localiza&#231;&#227;o das les&#245;es e contato&#44; melhoria com o afastamento e piora com retorno ao trabalho e teste de contato&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1&#8211;3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Neste estudo&#44; foram analisados&#58; a frequ&#234;ncia de DCO em pacientes submetidos aos testes de contato em ambulat&#243;rio n&#227;o especializado em DOs&#44; entre 2004 e 2017&#59; a distribui&#231;&#227;o por idade&#44; g&#234;nero&#44; atividade profissional e localiza&#231;&#227;o da dermatose&#59; os diagn&#243;sticos&#59; e os sensibilizantes mais comuns&#46; Os dados foram comparados com os dos n&#227;o portadores de DCO &#40;DCNO&#41; e o estudo foi aprovado no Comit&#234; de &#201;tica em Pesquisas&#44; 08077219&#46;1&#46;0000&#46;5479&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Foram coletados&#44; retrospectivamente&#44; os dados de 1&#46;405 pacientes testados com a bateria padr&#227;o brasileira &#40;FDA&#8208;Allergenic&#47;Brasil&#41;&#44; e fixados com contensores adequados&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Os dados foram analisados pelo programa SPSS vers&#227;o 13&#46;0&#44; e os resultados dos dois grupos foram comparados utilizando&#8208;se o Qui Quadrado &#40;p &#60; 0&#44;005&#41;&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Entre os 1&#46;405 testados&#44; 349 &#40;25&#44;3&#37;&#41; foram DCO e 1&#46;031 &#40;74&#44;4&#37;&#41;&#44; DCNO&#46; A maior frequ&#234;ncia de DCO quando comparada com publica&#231;&#227;o anterior &#40;10&#44;9&#37;&#41; pode refletir o aumento do n&#250;mero de subst&#226;ncias testadas e o envolvimento da Medicina Ocupacional na conclus&#227;o diagn&#243;stica&#46; Entretanto&#44; o n&#250;mero est&#225; abaixo da frequ&#234;ncia nacional &#40;34&#44;2&#37;&#41; dos casos de DO&#44; provavelmente por se tratar de servi&#231;o n&#227;o especializado nesse tipo de dermatoses&#46;<span class="elsevierStyleSup">4&#44;</span><a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">5</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Entre as DCOs&#44; 152 &#40;43&#44;6&#37;&#41; eram DAC&#44; 55 &#40;15&#44;8&#37;&#41; DCI&#44; 8 &#40;2&#44;3&#37;&#41; dermatite at&#243;pica &#40;DA&#41; e 215 &#40;61&#44;6&#37;&#41; outras dermatoses&#46; Entre as DCNO&#44; 455 &#40;44&#44;1&#37;&#41; eram DAC&#44; 70 &#40;6&#44;8&#37;&#41; DCI&#44; 54 &#40;5&#44;2&#37;&#41; DA e 452 &#40;43&#44;8&#37;&#41; outras dermatoses&#46; Dentre os diagn&#243;sticos&#44; a DAC foi o mais comum em ambos os grupos&#46; No entanto&#44; a DCI &#233; o subtipo mais comum em todo o mundo&#44; especialmente em casos ocupacionais&#44; com frequ&#234;ncia estatisticamente maior neste grupo &#40;p &#60; 0&#44;001&#41;&#46; A propor&#231;&#227;o desses diagn&#243;sticos varia de acordo com a regi&#227;o&#44; por diferen&#231;as em tipos de ind&#250;stria&#44; normas de regulamenta&#231;&#227;o&#44; sistemas de notifica&#231;&#227;o e disponibilidade de centros capacitados para testes de contato&#46; J&#225; a DA pode ser considerada DO&#44; uma vez que muitos trabalhadores pioram ap&#243;s contato com os al&#233;rgenos e irritantes do ambiente de trabalho&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Entre as DCOs&#44; a m&#233;dia das idades foi de 42&#44;1 anos&#44; enquanto nas DCNOs foi de 47&#44;5 anos &#40;p &#60; 0&#44;005&#41;&#44; gerando perdas aos sistemas produtivos e seguridade social&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Entre as DCOs havia 182 &#40;52&#44;1&#37;&#41; mulheres e 167 &#40;47&#44;9&#37;&#41; homens&#44; enquanto na DCNO eram 797 &#40;77&#44;3&#37;&#41; mulheres e 234 &#40;22&#44;7&#37;&#41; homens&#46; A frequ&#234;ncia de mulheres foi maior entre as DCNOs &#40;p &#60; 0&#44;005&#41;&#44; pois provavelmente representam a parcela da popula&#231;&#227;o que mais procura atendimento m&#233;dico&#44; mas significantemente menor no grupo ocupacional&#44; talvez pelo fato de haver mais trabalhadores homens nas atividades com exposi&#231;&#227;o a sensibilizantes e irritantes&#46; Al&#233;m disso&#44; as mulheres tendem a ser mais adeptas ao uso de equipamentos de prote&#231;&#227;o individual e cuidados preventivos&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">6</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">As profiss&#245;es mais prevalentes na DCO est&#227;o na <a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#44; e envolvem os profissionais com atividades &#250;midas &#40;contato com &#225;gua &#62; 2 horas di&#225;rias&#44; ou lavagens das m&#227;os &#62; 20 vezes no dia&#41; ou exposi&#231;&#227;o a conhecidos sensibilizantes e irritantes&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">7</span></a></p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0060" class="elsevierStylePara elsevierViewall">O tempo de evolu&#231;&#227;o da doen&#231;a na DCO foi de 29&#44;2 meses&#44; enquanto na DCNO foi de 39&#44;5 meses &#40;p &#60; 0&#44;005&#41;&#46; A dificuldade em manter as atividades laborais talvez tenha favorecido a busca por aux&#237;lio de maneira mais precoce nos casos de DCO&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Quanto &#224; localiza&#231;&#227;o da dermatose&#44; houve diferen&#231;a estat&#237;stica em rela&#231;&#227;o a DCO para m&#227;os &#40;regi&#245;es palmar e dorso&#41; e antebra&#231;os &#40;p &#60; 0&#44;001&#41;&#44; enquanto em portadores de DCNO a face foi a mais acometida &#40;582&#47;66&#44;7&#37;&#41;&#46; Essa diferen&#231;a &#233; esperada&#44; j&#225; que as DCOs acometem principalmente as m&#227;os&#44; que manipulam diretamente produtos irritantes ou sensibilizantes&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Os principais sensibilizantes relevantes observados nos dois grupos est&#227;o no <a class="elsevierStyleCrossRef" href="#tbl0010">tabela 2</a>&#59; o n&#237;quel &#233; o mais importante&#44; presente em atividades ocupacionais ou n&#227;o&#46; As m&#227;os s&#227;o acometidas em raz&#227;o do contato com ferramentas de trabalho&#44; como agulhas de costura&#44; pin&#231;as&#44; alicates de cut&#237;culas&#44; chaves e tesouras&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">O bicromato de pot&#225;ssio est&#225; relacionado aos pedreiros&#44; por sua presen&#231;a no cimento &#40;como contaminante&#44; resultante do processo de fabrica&#231;&#227;o&#41;&#44; e &#233; um importante al&#233;rgeno ocupacional em estudos semelhantes&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">8</span></a></p><p id="par0080" class="elsevierStylePara elsevierViewall">Os grupos tiuram&#44; carba e MBT s&#227;o agentes vulcanizadores da borracha&#44; comuns nas luvas&#44; utilizadas em diversos setores produtivos&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">A resina ep&#243;xi &#233; um material utilizado em diversos produtos como tintas&#44; acabamento para pisos&#44; fibras de vidro&#44; adesivos para metais&#44; madeiras e concreto&#46; Desse modo&#44; as les&#245;es surgem em v&#225;rias localiza&#231;&#245;es&#44; e medidas de prote&#231;&#227;o s&#227;o dif&#237;ceis&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">9</span></a></p><p id="par0090" class="elsevierStylePara elsevierViewall">Quaternium 15 &#40;conservante liberador de formalde&#237;do&#41;&#44; presente em produtos infantis&#44; cosm&#233;ticos&#44; shampoos de uso veterin&#225;rio&#44; materiais para polimento e ceras&#44; &#233; um al&#233;rgeno onipresente&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">10</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">Alguns al&#233;rgenos apresentaram altas frequ&#234;ncias nos dois grupos &#40;sem diferen&#231;a estat&#237;stica&#41;&#44; entre eles o Kathon CG&#58; DCO &#40;24&#47;6&#44;9&#37;&#41; e DCNO &#40;84&#47;8&#44;2&#37;&#41;&#44; mistura de conservantes de produtos aquosos como cosm&#233;ticos&#44; artigos de limpeza &#40;detergentes&#44; sab&#245;es&#44; &#243;leos lubrificantes&#41; e tintas&#44; tendo os casos ocupacionais ocorrido em trabalhadores de limpeza&#44; cabeleireiros e pintores&#59; e parafenilenodiamina&#44; corante das tinturas de cabelo&#58; DCO &#40;27&#47;7&#44;8&#37;&#41; e DCNO &#40;110&#47;10&#44;7&#37;&#41;&#44; cujos casos ocupacionais ocorreram em cabeleireiros&#44; acometendo as m&#227;os pela n&#227;o utiliza&#231;&#227;o adequada de EPIs&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">No per&#237;odo estudado&#44; a DCO representou 25&#44;3&#37; dos casos submetidos aos testes de contato&#59; o grupo de jovens do sexo masculino &#233; o mais afetado&#44; com impacto para a sa&#250;de do trabalhador e a economia do pa&#237;s&#46; O estudo das DCOs em nosso meio &#233; fundamental para o planejamento de a&#231;&#245;es de preven&#231;&#227;o e capacita&#231;&#227;o diagn&#243;stica dos centros dermatol&#243;gicos&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Suporte financeiro</span><p id="par0105" class="elsevierStylePara elsevierViewall">Nenhum&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Contribui&#231;&#227;o dos autores</span><p id="par0110" class="elsevierStylePara elsevierViewall">Rosana Lazzarini&#58; Concep&#231;&#227;o e planejamento do estudo&#59; elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; obten&#231;&#227;o&#44; an&#225;lise e interpreta&#231;&#227;o dos dados&#59; participa&#231;&#227;o efetiva na orienta&#231;&#227;o da pesquisa&#59; participa&#231;&#227;o intelectual em conduta proped&#234;utica e&#47;ou terap&#234;utica de casos estudados&#59; revis&#227;o cr&#237;tica da literatura&#59; revis&#227;o cr&#237;tica do manuscrito&#59; aprova&#231;&#227;o da vers&#227;o final do manuscrito&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">Mariana de Figueiredo Silva Hafner&#58; Concep&#231;&#227;o e planejamento do estudo&#59; elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; obten&#231;&#227;o&#44; an&#225;lise e interpreta&#231;&#227;o dos dados&#59; participa&#231;&#227;o efetiva na orienta&#231;&#227;o da pesquisa&#59; participa&#231;&#227;o intelectual em conduta proped&#234;utica e&#47;ou terap&#234;utica de casos estudados&#59; revis&#227;o cr&#237;tica da literatura&#59; revis&#227;o cr&#237;tica do manuscrito&#59; aprova&#231;&#227;o da vers&#227;o final do manuscrito&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Nathalie Mie Suzuki&#58; Participa&#231;&#227;o efetiva na orienta&#231;&#227;o da pesquisa&#59; participa&#231;&#227;o intelectual em conduta proped&#234;utica e&#47;ou terap&#234;utica de casos estudados&#59; revis&#227;o cr&#237;tica da literatura&#59; revis&#227;o cr&#237;tica do manuscrito&#59; aprova&#231;&#227;o da vers&#227;o final do manuscrito&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Isabela Marangon Pasotti&#58; Elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; obten&#231;&#227;o&#44; an&#225;lise e interpreta&#231;&#227;o dos dados&#59; aprova&#231;&#227;o da vers&#227;o final do manuscrito&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">Maria Regina de Paula Leite Kraft&#58; Elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; obten&#231;&#227;o&#44; an&#225;lise e interpreta&#231;&#227;o dos dados&#59; aprova&#231;&#227;o da vers&#227;o final do manuscrito&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflito de interesses</span><p id="par0135" class="elsevierStylePara elsevierViewall">Nenhum&#46;</p></span></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Como citar este artigo&#58; Lazzarini R&#44; Hafner MFS&#44; Suzuki NM&#44; Pasotti IM&#44; Kraft MRPL&#46; Occupational contact dermatitis&#58; analysis of cases observed in a service not specialized in occupational dermatosis between 2004 and 2017&#46; An Bras Dermatol&#46; 2022&#59;97&#58;105&#8211;7&#46;</p>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0010">Trabalho realizado na Cl&#237;nica de Dermatologia da Santa Casa de S&#227;o Paulo&#44; S&#227;o Paulo&#44; SP&#44; Brasil&#46;</p>"
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                  \t\t\t\t">Profissionais do lar&#47;limpeza&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">27&#44;3&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">72&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">20&#44;6&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">7&#44;4&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Total&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col">Al&#233;rgenos&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">p &#61; 0&#44;018&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">51&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">p &#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Tiuram mix&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">49&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">p &#60; 0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Resina ep&#243;xi&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Quaternium 15<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">p &#61; 0&#44;031&nbsp;\t\t\t\t\t\t\n
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                      "titulo" => "Occupational dermatosis"
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                        0 => array:2 [
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                          "autores" => array:3 [
                            0 => "O&#46; Alchorne Ade"
                            1 => "M&#46;M&#46; Alchorne"
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                    0 => array:2 [
                      "doi" => "10.1590/s0365-05962010000200003"
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                        "tituloSerie" => "An Bras Dermatol&#46;"
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                        "volumen" => "85"
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                      "titulo" => "Dermatite de contato"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "I&#46; Duarte"
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                            2 => "M&#46; Hafner"
                            3 => "N&#46;A&#46; Monteiro"
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                    0 => array:1 [
                      "LibroEditado" => array:4 [
                        "editores" => "W&#46;Belda Junior, N&#46;DiChiachio, P&#46;R&#46;Criado"
                        "titulo" => "Tratado de Dermatologia&#46;"
                        "edicion" => "3 ed&#46;"
                        "serieFecha" => "2018"
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                    0 => array:2 [
                      "titulo" => "The validity of the Mathias criteria for establishing occupational causation and aggravation of contact dermatitis"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Ingber"
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                    0 => array:2 [
                      "doi" => "10.1111/j.0105-1873.2004.00273.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Contact Dermatitis&#46;"
                        "fecha" => "2004"
                        "volumen" => "51"
                        "paginaInicial" => "9"
                        "paginaFinal" => "12"
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Informação do artigo
ISSN: 26662752
Idioma original: Português
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