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wound bed with a fibrotic and devitalized tissue&#44; without signs of colonization&#44; edge not adhered to the bed &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; The ulcer presented serous exudation and local pain with moderate intensity&#46; Palpable distal pulses 4&#43;&#47;4&#43;&#46; MEC was initiated &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41; with exchange of dressings twice a week for the first three weeks due to high exudation and saturation of the dressing and&#44; thereafter&#44; once a week&#46; On the first 20 days&#44; the VU became shallower&#44; with partially vitalized bed and edges adhered to the wound bed&#44; making possible the spacing of the dressing changes&#46; In a three-month period&#44; there was a significant improvement in the quality of the ulcer wound bed and a decrease in the ulcerated area until completes healing &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46; High compression elastic stockings were prescribed to prevent relapse&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">According to a systematic review on compression therapy for VU&#44; compression increases the healing rate&#46; The multilayer system is more effective than the traditional ones&#44; while high compression is more effective than low compression&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">There are two basic forms of compressive treatment for VU of the limbs&#58; inelastic &#40;Unna&#39;s boot&#41; and elastic &#40;bands&#44; elastic stockings and multilayer systems&#41;&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">MEC bandages usually have a protective orthopedic wool padding&#44; and may also include a crepe retention layer&#44; elastic compression bandage and cohesive elastic bandage to prevent slipping and keep the system in high compression during usage&#44; becoming effective&#44; because acts both in macro and microcirculation&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">The multilayer therapy is composed of 2&#8211;4 layers&#46; The following brands are available in Brazil&#58; UrgoK2&#174;&#44; Coban 2&#174;&#44; Jobst&#174; &#40;2 layers&#41;&#44; Dyna-flex&#174; &#40;3 layers&#41;&#44; Curatec K4&#174; and Profore&#174; by Smith &#38; Nephew&#174; &#40;4 layers&#41;&#46; The number of layers is not as essential as the ideal combination of different materials to maintain sustained compression&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">A correct diagnosis and exclusion of peripheral arterial disease is important for the indication of MEC&#46; The use of this therapy in patients with absence of distal pulses or ankle-arm index<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;9 is contraindicated&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">This system should remain on the limb for a maximum of seven days&#44; having the advantage of the maintenance of sustained high compression around the ankle throughout this time&#46; The compression should be from 35 to 40<span class="elsevierStyleHsp" style=""></span>mmHg and gradually lower in the region below the knee &#40;17<span class="elsevierStyleHsp" style=""></span>mmHg&#41;&#46; The patient must be stimulated to ambulate in order to achieve compression&#39;s benefits&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">MEC bandages should be applied by trained health professionals &#40;physicians and nurses&#41;&#44; because their effectiveness may be influenced by the application technique&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#44;4</span></a> The unit cost is still high&#44; but the cost&#47;benefit ratio is greater in relation to common dressings and other less effective therapies&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">The advantages of MECs are related to the patient&#39;s comfort&#44; tolerability and quality of life&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> There have been reports on improvement of pain&#44; easiness in performing daily activities and lesser discomfort during the day and during sleep&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a></p><p id="par0070" class="elsevierStylePara elsevierViewall">The MECs have demonstrated significant effectiveness in healing and comfort to the patient&#44; where our clinical case study demonstrated effectiveness in its use&#44; healing a VU with more than 30 years&#46; This corroborates the systematic reviews regarding the indication of this method&#44; favoring a faster healing with good cost&#8211;benefit ratio&#46;</p><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Financial support</span><p id="par0090" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Authors&#8217; contributions</span><p id="par0075" class="elsevierStylePara elsevierViewall">Bruna Cristina Velozo&#58; Elaboration and writing of the manuscript&#59; obtaining&#44; analysis&#44; and interpretation of the data&#59; critical review of the literature&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Raquel Colenci&#58; Effective participation in research orientation&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Luciana Patr&#237;cia Fernandes Abbade&#58; Approval of the final version of the manuscript&#59; conception and planning of the study&#59; elaboration and writing of the manuscript&#59; effective participation in research orientation&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflicts of interest</span><p id="par0095" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span></span>"
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Case Letter
Multilayer elastic compression for the treatment of a 30-year venous ulcer
Bruna Cristina Velozoa,
Autor para correspondência
brunavelozo_sm@homail.com

Corresponding author.
, Raquel Colencia, Luciana Patrícia Fernandes Abbadeb
a Department of Nursing, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista Júlio de, Botucatu, SP, Brazil
b Department of Dermatology and Radiotherapy, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brazil
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Venous Ulcers &#40;VU&#41; are a significant burden for both patients and the health system&#46; Their prevalence and complexity are expected to increase over the years&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The gold standard of treatment for VU&#44; i&#46;e&#46;&#44; with a high level of evidence based on systematic reviews&#44; is multilayer elastic compression &#40;MEC&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Although MEC bandages are increasingly used in practice&#44; they remain neglected in many international consensus documents and guidelines related to compression&#46; Added to this&#44; this therapy is not available in the Brazilian Unified Health System&#44; hampering access of the treatment to all patients&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">A clinical case with use of MEC in a 73 years old female patient&#44; with a history of post-thrombotic VU of the left lower limb &#40;LLL&#41; for more than 30 years&#44; is reported&#46; Throughout this period several forms of clinical treatments were followed&#58; debridement&#44; local dressings &#40;activated charcoal&#44; hydrofiber silver dressing&#44; hydrogels&#41; and compressive treatment with Unna&#8217;s boot and elastic band&#44; without healing of the ulcer&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">At the initial examination&#44; an ulcer in the posterior and lateral regions of the LLL was observed with 15<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>8<span class="elsevierStyleHsp" style=""></span>cm&#44; wound bed with a fibrotic and devitalized tissue&#44; without signs of colonization&#44; edge not adhered to the bed &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; The ulcer presented serous exudation and local pain with moderate intensity&#46; Palpable distal pulses 4&#43;&#47;4&#43;&#46; MEC was initiated &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41; with exchange of dressings twice a week for the first three weeks due to high exudation and saturation of the dressing and&#44; thereafter&#44; once a week&#46; On the first 20 days&#44; the VU became shallower&#44; with partially vitalized bed and edges adhered to the wound bed&#44; making possible the spacing of the dressing changes&#46; In a three-month period&#44; there was a significant improvement in the quality of the ulcer wound bed and a decrease in the ulcerated area until completes healing &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46; High compression elastic stockings were prescribed to prevent relapse&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">According to a systematic review on compression therapy for VU&#44; compression increases the healing rate&#46; The multilayer system is more effective than the traditional ones&#44; while high compression is more effective than low compression&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">There are two basic forms of compressive treatment for VU of the limbs&#58; inelastic &#40;Unna&#39;s boot&#41; and elastic &#40;bands&#44; elastic stockings and multilayer systems&#41;&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">MEC bandages usually have a protective orthopedic wool padding&#44; and may also include a crepe retention layer&#44; elastic compression bandage and cohesive elastic bandage to prevent slipping and keep the system in high compression during usage&#44; becoming effective&#44; because acts both in macro and microcirculation&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">The multilayer therapy is composed of 2&#8211;4 layers&#46; The following brands are available in Brazil&#58; UrgoK2&#174;&#44; Coban 2&#174;&#44; Jobst&#174; &#40;2 layers&#41;&#44; Dyna-flex&#174; &#40;3 layers&#41;&#44; Curatec K4&#174; and Profore&#174; by Smith &#38; Nephew&#174; &#40;4 layers&#41;&#46; The number of layers is not as essential as the ideal combination of different materials to maintain sustained compression&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">A correct diagnosis and exclusion of peripheral arterial disease is important for the indication of MEC&#46; The use of this therapy in patients with absence of distal pulses or ankle-arm index<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;9 is contraindicated&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">This system should remain on the limb for a maximum of seven days&#44; having the advantage of the maintenance of sustained high compression around the ankle throughout this time&#46; The compression should be from 35 to 40<span class="elsevierStyleHsp" style=""></span>mmHg and gradually lower in the region below the knee &#40;17<span class="elsevierStyleHsp" style=""></span>mmHg&#41;&#46; The patient must be stimulated to ambulate in order to achieve compression&#39;s benefits&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">MEC bandages should be applied by trained health professionals &#40;physicians and nurses&#41;&#44; because their effectiveness may be influenced by the application technique&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#44;4</span></a> The unit cost is still high&#44; but the cost&#47;benefit ratio is greater in relation to common dressings and other less effective therapies&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">The advantages of MECs are related to the patient&#39;s comfort&#44; tolerability and quality of life&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> There have been reports on improvement of pain&#44; easiness in performing daily activities and lesser discomfort during the day and during sleep&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a></p><p id="par0070" class="elsevierStylePara elsevierViewall">The MECs have demonstrated significant effectiveness in healing and comfort to the patient&#44; where our clinical case study demonstrated effectiveness in its use&#44; healing a VU with more than 30 years&#46; This corroborates the systematic reviews regarding the indication of this method&#44; favoring a faster healing with good cost&#8211;benefit ratio&#46;</p><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Financial support</span><p id="par0090" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Authors&#8217; contributions</span><p id="par0075" class="elsevierStylePara elsevierViewall">Bruna Cristina Velozo&#58; Elaboration and writing of the manuscript&#59; obtaining&#44; analysis&#44; and interpretation of the data&#59; critical review of the literature&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Raquel Colenci&#58; Effective participation in research orientation&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Luciana Patr&#237;cia Fernandes Abbade&#58; Approval of the final version of the manuscript&#59; conception and planning of the study&#59; elaboration and writing of the manuscript&#59; effective participation in research orientation&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflicts of interest</span><p id="par0095" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span></span>"
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