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refletindo prov&#225;veis dificuldades para defini&#231;&#227;o diagn&#243;stica e alongando&#44; assim&#44; o tempo de doen&#231;a pelo n&#227;o afastamento dos agentes causais&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">As regi&#245;es mais afetadas nos pacientes foram&#58; couro cabeludo em 12 casos &#40;60&#37;&#41;&#44; face e membros superiores em 10 &#40;50&#37;&#41; cada&#44; cervical em sete &#40;35&#37;&#41;&#44; dorso em quatro &#40;20&#37;&#41;&#44; orelhas em tr&#234;s &#40;15&#37;&#41;&#44; t&#243;rax e axilas em dois &#40;10&#37;&#41; cada&#44; abdome e ombros em um &#40;5&#37;&#41; cada&#44; dados esses compat&#237;veis com a literatura&#46; Essa variedade de poss&#237;veis apresenta&#231;&#245;es cl&#237;nicas contribui para dificuldades diagn&#243;sticas&#44; ainda mais quando n&#227;o h&#225; les&#245;es evidentes no couro cabeludo&#44; como ocorreu em oito dos 20 pacientes &#40;40&#37;&#41;&#44; o que pode ser explicado pelas caracter&#237;sticas anat&#244;micas da regi&#227;o &#40;grande espessura e maior n&#250;mero de unidades piloseb&#225;ceas&#41;&#44; que acabam dificultando a penetra&#231;&#227;o dos al&#233;rgenos e a detec&#231;&#227;o do eczema&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#44;2</span></a> Em alguns pacientes&#44; as les&#245;es comprometiam as &#225;reas que entram em contato com o xampu ao ser enxaguado&#58; fronte&#44; p&#225;lpebras&#44; regi&#227;o auricular&#44; cervical lateral e dorso &#40;<a class="elsevierStyleCrossRefs" href="#fig0005">figs&#46; 1&#8208;3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">Os resultados positivos e relevantes dos testes de contato est&#227;o apresentados na <a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#46; Os al&#233;rgenos respons&#225;veis foram conservantes &#40;Kathon CG&#44; formalde&#237;do&#44; captan&#44; metildibromoglutaronitrila e diazolinidilureia&#41;&#44; fragr&#226;ncias &#40;fragr&#226;ncia mix 1 &#91;FM1&#93; e fragr&#226;ncia mix 2 &#91;FM2&#93; e b&#225;lsamo do Peru&#41; e surfactantes &#40;cocoamidopropilbeta&#237;na&#44; laurilpoliglucos&#237;deo e decilglucos&#237;deo&#41;&#46; Esses resultados coincidem com estudos da literatura&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> Destaca&#8208;se que entre os 11 al&#233;rgenos causadores de DAC apresentados&#44; apenas quatro est&#227;o na bateria padr&#227;o brasileira &#40;Kathon CG&#44; formalde&#237;do&#44; fragr&#226;ncia&#8208;mix&#160;1 e b&#225;lsamo do Peru&#41;&#44; enquanto os demais est&#227;o nas baterias complementares usadas&#46; Em todos os casos o diagn&#243;stico foi confirmado pelo resultado do teste com relev&#226;ncia atual&#44; verificada pela leitura dos r&#243;tulos dos xampus usados &#40;comprovou a exposi&#231;&#227;o aos al&#233;rgenos detectados&#41; e a melhoria completa ap&#243;s afastamento desses agentes no seguimento cl&#237;nico&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0055" class="elsevierStylePara elsevierViewall">Como a maioria dos xampus tem composi&#231;&#245;es semelhantes&#44; &#233; comum que os pacientes mantenham a dermatite mesmo ap&#243;s trocar o produto e a marca por conta pr&#243;pria&#46; Dessa forma&#44; &#233; essencial indicar teste de contato sempre que houver suspeita cl&#237;nica e este deve ser feito com a s&#233;rie padr&#227;o e as complementares&#44; o que possibilita assim a orienta&#231;&#227;o individualizada a cada paciente quanto &#224; por outros produtos espec&#237;ficos&#46;</p><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Suporte financeiro</span><p id="par0090" class="elsevierStylePara elsevierViewall">Nenhum&#46;</p></span><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Contribui&#231;&#227;o dos autores</span><p id="par0060" class="elsevierStylePara elsevierViewall">Rosana Lazzarini&#58; Aprova&#231;&#227;o da vers&#227;o final do manuscrito&#59; concep&#231;&#227;o e planejamento do estudo&#59; participa&#231;&#227;o efetiva na orienta&#231;&#227;o da pesquisa&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Lilian Lemos Costa&#58; Obten&#231;&#227;o&#44; an&#225;lise e interpreta&#231;&#227;o dos dados&#59; revis&#227;o cr&#237;tica da literatura&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Nathalie Mie Suzuki&#58; Elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; revis&#227;o cr&#237;tica do manuscrito&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Mariana de Figueiredo Silva Hafner&#58; Concep&#231;&#227;o e planejamento do estudo&#59; elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; revis&#227;o cr&#237;tica do manuscrito&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflitos de interesse</span><p id="par0085" class="elsevierStylePara elsevierViewall">Nenhum&#46;</p></span></span>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Al&#233;rgenos relevantes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">N&#250;mero de testes positivos&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Kathon CG<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Formalde&#237;do&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Cocamidopropilbetaina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Captan<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">b</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Laurilpoliglucosideo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Decilglucosideo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Metildibromoglutaronitrila&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">FM1<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">FM2<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Diazolinidilureia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&#225;lsamo do Peru&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Total&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">47<a class="elsevierStyleCrossRef" href="#tblfn0025"><span class="elsevierStyleSup">e</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">100&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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Carta – Investigação
Dermatite alérgica de contato por componentes de xampus: análise descritiva de 20 casos
Rosana Lazzarinia, Lilian Lemos Costab, Nathalie Mie Suzukia, Mariana de Figueiredo Silva Hafnera,
Corresponding author
mariana@hafner.med.br

Autor para correspondência.
a Setor de Alergias, Clínica de Dermatologia, Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil
b Clínica de Dermatologia, Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brasil
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0010" class="elsevierStylePara elsevierViewall">Os xampus s&#227;o os cosm&#233;ticos mais usados para cuidados com cabelos e couro cabeludo&#46; S&#227;o compostos por diversos ingredientes&#44; em geral de&#160;10&#160;a&#160;30&#44; com diferentes fun&#231;&#245;es&#44; como surfactantes que atuam na limpeza &#40;emulsifica&#231;&#227;o&#41;&#44; conservantes que estabilizam o produto e fragr&#226;ncias que o tornam cosmeticamente agrad&#225;vel ao consumidor&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#8211;3</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Rea&#231;&#245;es adversas ao seu uso podem ocorrer&#46; Embora estudos mostrem que o poder de sensibiliza&#231;&#227;o dos al&#233;rgenos presentes em produtos enxagu&#225;veis seja menor &#40;pelo contato ef&#234;mero com a pele&#41;&#44; a dermatite al&#233;rgica de contato &#40;DAC&#41; por componentes dos xampus &#233; bem descrita&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a> &#201; poss&#237;vel que a sensibiliza&#231;&#227;o ocorra anteriormente pelo contato com outros produtos que contenham os mesmos al&#233;rgenos&#46; Al&#233;m disso&#44; fatores como frequ&#234;ncia de uso e presen&#231;a de atopia poderiam influenciar na ocorr&#234;ncia do processo&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Os principais sintomas referidos s&#227;o prurido e queda de cabelos&#46; Les&#245;es eczematosas geralmente ocorrem em couro cabeludo&#44; face&#44; orelhas e regi&#227;o cervical&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#44;5</span></a> Nesses casos&#44; o teste de contato &#233; a principal ferramenta para identifica&#231;&#227;o do agente causal e ent&#227;o&#44; cura do processo&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">O objetivo deste estudo foi avaliar os principais al&#233;rgenos causadores da DAC por xampus e as caracter&#237;sticas epidemiol&#243;gicas da popula&#231;&#227;o acometida por essa afec&#231;&#227;o&#44; em servi&#231;o dermatol&#243;gico especializado de hospital quatern&#225;rio&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Foram feitos 654 testes de contato entre janeiro de&#160;2014 e agosto de&#160;2019&#46; Entre esses&#44; foram escolhidos aqueles com diagn&#243;stico final de DAC por xampu para an&#225;lise&#46; As baterias usadas em todos os testes dos casos selecionados foram padr&#227;o brasileiro &#40;FDA Allergenic&#44; Brasil&#41;&#44; capilar &#40;IPI ASAC&#44; Brasil&#41; e latino&#8208;americana &#40;Chemothecnique&#44; Su&#233;cia&#41;&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Foram encontrados 20 pacientes com diagn&#243;stico de DAC por xampus &#40;3&#37; dos submetidos a teste de contato&#41;&#46; Desses&#44; 19 &#40;95&#37;&#41; eram do g&#234;nero feminino e um do masculino&#46; A m&#233;dia foi de 52&#44;2 anos&#46; A maior frequ&#234;ncia de pacientes do sexo feminino &#233; consistente com o maior uso de cosm&#233;ticos por esse grupo&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">O tempo m&#233;dio da doen&#231;a foi de 46 meses&#44; refletindo prov&#225;veis dificuldades para defini&#231;&#227;o diagn&#243;stica e alongando&#44; assim&#44; o tempo de doen&#231;a pelo n&#227;o afastamento dos agentes causais&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">As regi&#245;es mais afetadas nos pacientes foram&#58; couro cabeludo em 12 casos &#40;60&#37;&#41;&#44; face e membros superiores em 10 &#40;50&#37;&#41; cada&#44; cervical em sete &#40;35&#37;&#41;&#44; dorso em quatro &#40;20&#37;&#41;&#44; orelhas em tr&#234;s &#40;15&#37;&#41;&#44; t&#243;rax e axilas em dois &#40;10&#37;&#41; cada&#44; abdome e ombros em um &#40;5&#37;&#41; cada&#44; dados esses compat&#237;veis com a literatura&#46; Essa variedade de poss&#237;veis apresenta&#231;&#245;es cl&#237;nicas contribui para dificuldades diagn&#243;sticas&#44; ainda mais quando n&#227;o h&#225; les&#245;es evidentes no couro cabeludo&#44; como ocorreu em oito dos 20 pacientes &#40;40&#37;&#41;&#44; o que pode ser explicado pelas caracter&#237;sticas anat&#244;micas da regi&#227;o &#40;grande espessura e maior n&#250;mero de unidades piloseb&#225;ceas&#41;&#44; que acabam dificultando a penetra&#231;&#227;o dos al&#233;rgenos e a detec&#231;&#227;o do eczema&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#44;2</span></a> Em alguns pacientes&#44; as les&#245;es comprometiam as &#225;reas que entram em contato com o xampu ao ser enxaguado&#58; fronte&#44; p&#225;lpebras&#44; regi&#227;o auricular&#44; cervical lateral e dorso &#40;<a class="elsevierStyleCrossRefs" href="#fig0005">figs&#46; 1&#8208;3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">Os resultados positivos e relevantes dos testes de contato est&#227;o apresentados na <a class="elsevierStyleCrossRef" href="#tbl0005">tabela 1</a>&#46; Os al&#233;rgenos respons&#225;veis foram conservantes &#40;Kathon CG&#44; formalde&#237;do&#44; captan&#44; metildibromoglutaronitrila e diazolinidilureia&#41;&#44; fragr&#226;ncias &#40;fragr&#226;ncia mix 1 &#91;FM1&#93; e fragr&#226;ncia mix 2 &#91;FM2&#93; e b&#225;lsamo do Peru&#41; e surfactantes &#40;cocoamidopropilbeta&#237;na&#44; laurilpoliglucos&#237;deo e decilglucos&#237;deo&#41;&#46; Esses resultados coincidem com estudos da literatura&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> Destaca&#8208;se que entre os 11 al&#233;rgenos causadores de DAC apresentados&#44; apenas quatro est&#227;o na bateria padr&#227;o brasileira &#40;Kathon CG&#44; formalde&#237;do&#44; fragr&#226;ncia&#8208;mix&#160;1 e b&#225;lsamo do Peru&#41;&#44; enquanto os demais est&#227;o nas baterias complementares usadas&#46; Em todos os casos o diagn&#243;stico foi confirmado pelo resultado do teste com relev&#226;ncia atual&#44; verificada pela leitura dos r&#243;tulos dos xampus usados &#40;comprovou a exposi&#231;&#227;o aos al&#233;rgenos detectados&#41; e a melhoria completa ap&#243;s afastamento desses agentes no seguimento cl&#237;nico&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0055" class="elsevierStylePara elsevierViewall">Como a maioria dos xampus tem composi&#231;&#245;es semelhantes&#44; &#233; comum que os pacientes mantenham a dermatite mesmo ap&#243;s trocar o produto e a marca por conta pr&#243;pria&#46; Dessa forma&#44; &#233; essencial indicar teste de contato sempre que houver suspeita cl&#237;nica e este deve ser feito com a s&#233;rie padr&#227;o e as complementares&#44; o que possibilita assim a orienta&#231;&#227;o individualizada a cada paciente quanto &#224; por outros produtos espec&#237;ficos&#46;</p><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Suporte financeiro</span><p id="par0090" class="elsevierStylePara elsevierViewall">Nenhum&#46;</p></span><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Contribui&#231;&#227;o dos autores</span><p id="par0060" class="elsevierStylePara elsevierViewall">Rosana Lazzarini&#58; Aprova&#231;&#227;o da vers&#227;o final do manuscrito&#59; concep&#231;&#227;o e planejamento do estudo&#59; participa&#231;&#227;o efetiva na orienta&#231;&#227;o da pesquisa&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Lilian Lemos Costa&#58; Obten&#231;&#227;o&#44; an&#225;lise e interpreta&#231;&#227;o dos dados&#59; revis&#227;o cr&#237;tica da literatura&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Nathalie Mie Suzuki&#58; Elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; revis&#227;o cr&#237;tica do manuscrito&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Mariana de Figueiredo Silva Hafner&#58; Concep&#231;&#227;o e planejamento do estudo&#59; elabora&#231;&#227;o e reda&#231;&#227;o do manuscrito&#59; revis&#227;o cr&#237;tica do manuscrito&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflitos de interesse</span><p id="par0085" class="elsevierStylePara elsevierViewall">Nenhum&#46;</p></span></span>"
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                  \t\t\t\t">Decilglucosideo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Metildibromoglutaronitrila&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">FM1<a class="elsevierStyleCrossRef" href="#tblfn0015"><span class="elsevierStyleSup">c</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">FM2<a class="elsevierStyleCrossRef" href="#tblfn0020"><span class="elsevierStyleSup">d</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Diazolinidilureia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&#225;lsamo do Peru&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Total&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">47<a class="elsevierStyleCrossRef" href="#tblfn0025"><span class="elsevierStyleSup">e</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">100&#44;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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            0 => array:3 [
              "identificador" => "tblfn0005"
              "etiqueta" => "a"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Kathon CG&#58; metilisotiazolinona<span class="elsevierStyleHsp" style=""></span>&#43;<span class="elsevierStyleHsp" style=""></span>metilcloroisotiazolinona&#46;</p>"
            ]
            1 => array:3 [
              "identificador" => "tblfn0010"
              "etiqueta" => "b"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0010">Captan&#58; N&#8208;trichloromethylthio&#8208;4&#8208;cyclohexene&#8208;1&#44;2&#8208;dicarboximide&#46;</p>"
            ]
            2 => array:3 [
              "identificador" => "tblfn0015"
              "etiqueta" => "c"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0015">FM1&#58; geraniol&#44; cinnamaldehyde&#44; hydroxycitronellal&#44; cinnamyl alcohol&#44; amylcinnamaldehyde&#44; isoeugenol&#44; eugenol and oak moss&#46;</p>"
            ]
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              "identificador" => "tblfn0020"
              "etiqueta" => "d"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0020">FM2&#58; coumarin&#44; lyral&#44; citronellol&#44; farnesol&#44; citral&#44; hexylcinnamicaldehyde&#46;</p>"
            ]
            4 => array:3 [
              "identificador" => "tblfn0025"
              "etiqueta" => "e"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0025">OBS&#58; alguns pacientes tiveram mais de um teste positivo&#46;</p>"
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          "pt" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Al&#233;rgenos relevantes encontrados nos testes de contato</p>"
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Article information
ISSN: 26662752
Original language: Portuguese
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Idiomas
Anais Brasileiros de Dermatologia
en pt
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