Letter - Clinical
Pigmented polypoid basal cell carcinoma: a rare clinicopathological variant
Lido
2078
Vezesque se leu este artigo
592
Total PDF
1486
Total HTML
Compartilhar estatísticas
array:23 [ "pii" => "S0365059624001016" "issn" => "03650596" "doi" => "10.1016/j.abd.2023.03.011" "estado" => "S300" "fechaPublicacion" => "2024-09-01" "aid" => "960" "copyright" => "Sociedade Brasileira de Dermatologia" "copyrightAnyo" => "2024" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "pt" => array:18 [ "pii" => "S2666275224001206" "issn" => "26662752" "doi" => "10.1016/j.abdp.2024.05.011" "estado" => "S300" "fechaPublicacion" => "2024-09-01" "aid" => "960" "copyright" => "Sociedade Brasileira de Dermatologia" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "pt" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Cartas ‐ Caso clínico</span>" "titulo" => "Carcinoma basocelular polipoide pigmentado: rara variante clinicopatológica" "tienePdf" => "pt" "tieneTextoCompleto" => "pt" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "755" "paginaFinal" => "757" ] ] "contieneTextoCompleto" => array:1 [ "pt" => true ] "contienePdf" => array:1 [ "pt" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1727 "Ancho" => 2333 "Tamanyo" => 560833 ] ] "descripcion" => array:1 [ "pt" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A‐B) Visão frontal e tangencial da tumoração pedunculada exofítica de 40<span class="elsevierStyleHsp" style=""></span>mm no maior diâmetro. Superfície eritematosa, brilhante, perolada, e áreas pigmentadas na periferia.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Bruno de Carvalho Fantini, Cecilia Anatriello dos Santos, Sebastião Antônio de Barros Junior, Cacilda da Silva Souza" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Bruno de Carvalho" "apellidos" => "Fantini" ] 1 => array:2 [ "nombre" => "Cecilia Anatriello dos" "apellidos" => "Santos" ] 2 => array:2 [ "nombre" => "Sebastião Antônio de Barros" "apellidos" => "Junior" ] 3 => array:2 [ "nombre" => "Cacilda da Silva" "apellidos" => "Souza" ] ] ] ] ] "idiomaDefecto" => "pt" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S0365059624001016" "doi" => "10.1016/j.abd.2023.03.011" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059624001016?idApp=UINPBA00008Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275224001206?idApp=UINPBA00008Z" "url" => "/26662752/0000009900000005/v2_202409060549/S2666275224001206/v2_202409060549/pt/main.assets" ] ] "itemSiguiente" => array:18 [ "pii" => "S0365059624001107" "issn" => "03650596" "doi" => "10.1016/j.abd.2023.04.012" "estado" => "S300" "fechaPublicacion" => "2024-09-01" "aid" => "969" "copyright" => "Sociedade Brasileira de Dermatologia" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter - Clinical</span>" "titulo" => "Severe aggravation and possible triggering of pemphigus vulgaris following COVID-19 vaccination: report of two cases" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "758" "paginaFinal" => "762" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0020" "etiqueta" => "Figure 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 1203 "Ancho" => 3175 "Tamanyo" => 962832 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0020" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">(A) Histopathological findings showing acantholysis within the lower epidermal layers, and the presence of dense lymphocytic and neutrophilic dermal infiltrates (×40). (B) Direct immunofluorescence revealed intercellular deposition of IgG in the lower epidermal cells (×40).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Kinuko Irie, Toshiyuki Yamamoto" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Kinuko" "apellidos" => "Irie" ] 1 => array:2 [ "nombre" => "Toshiyuki" "apellidos" => "Yamamoto" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "pt" => array:9 [ "pii" => "S2666275224001292" "doi" => "10.1016/j.abdp.2024.05.020" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275224001292?idApp=UINPBA00008Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059624001107?idApp=UINPBA00008Z" "url" => "/03650596/0000009900000005/v2_202409130645/S0365059624001107/v2_202409130645/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0365059624001077" "issn" => "03650596" "doi" => "10.1016/j.abd.2022.12.015" "estado" => "S300" "fechaPublicacion" => "2024-09-01" "aid" => "966" "copyright" => "Sociedade Brasileira de Dermatologia" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter - Clinical</span>" "titulo" => "Neutrophilic dermatosis of the dorsal hands in a Mexican woman" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "753" "paginaFinal" => "755" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1471 "Ancho" => 3175 "Tamanyo" => 1286795 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">(A) Ulceration with entire epidermal necrosis (Hematoxylin & eosin, ×100). (B) Close-up view of the intense inflammatory infiltrate of neutrophils and lymphocytes with vasculitis through the dermis (Hematoxylin & eosin, ×400).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Carlos Barrera-Ochoa, Luis Enrique Cano-Aguilar, Hector Cantú-Maltos, Hector Proy-Trujillo, Nixma Eljure-López, María Elisa Vega-Memije" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Carlos" "apellidos" => "Barrera-Ochoa" ] 1 => array:2 [ "nombre" => "Luis Enrique" "apellidos" => "Cano-Aguilar" ] 2 => array:2 [ "nombre" => "Hector" "apellidos" => "Cantú-Maltos" ] 3 => array:2 [ "nombre" => "Hector" "apellidos" => "Proy-Trujillo" ] 4 => array:2 [ "nombre" => "Nixma" "apellidos" => "Eljure-López" ] 5 => array:2 [ "nombre" => "María Elisa" "apellidos" => "Vega-Memije" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "pt" => array:9 [ "pii" => "S2666275224001267" "doi" => "10.1016/j.abdp.2024.05.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275224001267?idApp=UINPBA00008Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059624001077?idApp=UINPBA00008Z" "url" => "/03650596/0000009900000005/v2_202409130645/S0365059624001077/v2_202409130645/en/main.assets" ] "en" => array:17 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter - Clinical</span>" "titulo" => "Pigmented polypoid basal cell carcinoma: a rare clinicopathological variant" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">Dear Editor,</span>" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "755" "paginaFinal" => "757" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Bruno de Carvalho Fantini, Cecilia Anatriello dos Santos, Sebastião Antônio de Barros Junior, Cacilda da Silva Souza" "autores" => array:4 [ 0 => array:3 [ "nombre" => "Bruno de Carvalho" "apellidos" => "Fantini" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "Cecilia Anatriello dos" "apellidos" => "Santos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "Sebastião Antônio de" "apellidos" => "Barros Junior" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0015" ] ] ] 3 => array:4 [ "nombre" => "Cacilda da" "apellidos" => "Silva Souza" "email" => array:1 [ 0 => "cssouza@fmrp.usp.br" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Department of Internal Medicine, Ribeirão Preto Faculty of Medicine, Universidade de São Paulo, Ribeirão Preto, SP, Brazil" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Department of Pathology and Forensic Medicine, Ribeirão Preto Faculty of Medicine Universidade de São Paulo, Ribeirão Preto, SP, Brazil" "etiqueta" => "b" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1150 "Ancho" => 2083 "Tamanyo" => 277560 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">On histopathology, a panoramic view showed a polypoid tumor consisting of basaloid neoplastic aggregations of varyng sizes and shapes with peripheral palisading, limited to the upper and middle part of the polyp.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Polypoid basal cell carcinoma (BCC) is a rare entity that is clinically distinct from other BCC subtypes, as it is pedunculated and connected by a stalk to the surface of the skin, and histopathology, exhibits tumor aggregates restricted to the exophytic polypoid area.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">A 69-year-old Caucasian man reported a rapidly growing pigmented lesion, about a year ago, on the lateral side of his right leg (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>), which he associated with local trauma. He denied excessive sun exposure. On dermatological examination, he had a tumor with an erythematous and shiny surface in the center, and pigmented on the periphery, measuring 40 mm in its largest diameter, pedunculated, transluminescent and of fibrous consistency (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>A). Dermoscopy showed large blue-gray ovoid nests on the periphery of the lesion and short white lines (chrysalises) across the entire surface, but without arboriform telangiectasias (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>B). There were no lymph node enlargements. Following excision, histopathology showed, in a panoramic view, a polypoid tumor consisting of basaloid neoplastic aggregations with peripheral palisading, varying in size, shape and pigment distribution, limites to the upper and middle part of the polyp (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>; <a class="elsevierStyleCrossRef" href="#fig0020">Fig. 4</a>A-B). The immunohistochemical markers Melan-A and HMB45 were negative. It was concluded that it was a nodular, cribriform, cystic, pigmented basal cell carcinoma with free surgical margins. The option for closure by secondary intention until diagnostic confirmation resulted in good evolution, with no signs of recurrence or metastasis up to three months of follow-up.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">The combination of reviews in the English and Japanese literature recorded just over 30 cases. In these reviews, the tumors varied between 10 mm and 80 mm in their largest diameter, and the size of the reported polyp was considered large.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2,3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Despite their large size, most lesions showed well-circumscribed nodules, without an aggressive infiltration pattern, and the neoplasm were restricted to the polypoid area. Distinctly, these polypoid BCCs predominated on the scalp and in the genital, perianal, or gluteal regions; followed by the trunk, face and perioptic regions, with 13% of cases found in the extremities.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,4</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The polypoid, sessile, or pedunculated shape of the neoplasm must be differentiated from Pinkus fibroepithelioma, a variant of the spectrum between BCC and trichoblastoma, presenting a peculiar and unmistakable histopathology.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">In conclusion, polypoid BCC has been recognized as a variant of nodular BCC based on its clinical, morphological, and histopathological peculiarities; additionally, its preferential locations suggest other etiological factors, in addition to the recognized exposure to ultraviolet radiation associated with BCCs.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1–4</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Financial support</span><p id="par0035" class="elsevierStylePara elsevierViewall">None declared.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Authors' contributions</span><p id="par0040" class="elsevierStylePara elsevierViewall">Bruno de Carvalho Fantini: Design of the case study, data survey, collection, or analysis and interpretation of data; intellectual participation in the propaedeutic and/or therapeutic conduct of the studied case; approval of the final version of the manuscript.</p><p id="par0045" class="elsevierStylePara elsevierViewall">Cecilia Anatriello dos Santos: Data survey, collection, or analysis, and interpretation of data; intellectual participation in the propaedeutic and/or therapeutic conduct of the studied case; approval of the final version of the manuscript.</p><p id="par0050" class="elsevierStylePara elsevierViewall">Sebastião Antônio de Barros Junior: Data survey, collection, or analysis and interpretation of data; approval of the final version of the manuscript.</p><p id="par0055" class="elsevierStylePara elsevierViewall">Cacilda da Silva Souza: Design and planning of the studied case; data survey, collection or analysis, and interpretation of data; drafting and editing of the manuscript or critical review of intellectual content; intellectual participation in the propaedeutic and/or therapeutic conduct of the studied case; critical review of the literature; approval of the final version of the manuscript.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflicts of interest</span><p id="par0060" class="elsevierStylePara elsevierViewall">None declared.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:4 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Financial support" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Authors' contributions" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Conflicts of interest" ] 3 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2023-02-04" "fechaAceptado" => "2023-03-11" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "⋆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Study conducted at the Hospital das Clínicas, Ribeirão Preto Faculty of Medicine, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.</p>" ] ] "multimedia" => array:4 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1727 "Ancho" => 2333 "Tamanyo" => 560833 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A‒B) Lateral and frontal view of the exophytic pedunculated tumor, 40-mm in its largest diameter, showing an erythematous, shiny, pearly surface, and pigmented areas on the periphery.</p>" ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1266 "Ancho" => 2341 "Tamanyo" => 219745 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">(A) Transillumination testing of the polypoid tumor. (B) On dermoscopy, large blue-grey ovoid nests on the periphery of the lesion can be observed, with white shiny areas and lines (chrysalises) predominating in the center, without arboriform telangiectasias.</p>" ] ] 2 => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1150 "Ancho" => 2083 "Tamanyo" => 277560 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">On histopathology, a panoramic view showed a polypoid tumor consisting of basaloid neoplastic aggregations of varyng sizes and shapes with peripheral palisading, limited to the upper and middle part of the polyp.</p>" ] ] 3 => array:8 [ "identificador" => "fig0020" "etiqueta" => "Figure 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 1562 "Ancho" => 2341 "Tamanyo" => 974317 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0020" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">(A‒B) Detail of basaloid neoplastic aggregations with peripheral palisading, and areas of melanin deposition (Hematoxylin & eosin, ×40, ×100, respectively).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Polypoid basal cell carcinoma: a new clinicopathological variant" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Megahed" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1046/j.1365-2133.1999.02774.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1999" "volumen" => "140" "paginaInicial" => "701" "paginaFinal" => "703" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10233325" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Polypoid Basal cell carcinoma on the perianal region: a case report and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "N. Misago" 1 => "Y. Narisawa" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1346-8138.2004.tb00505.x" "Revista" => array:6 [ "tituloSerie" => "J Dermatol" "fecha" => "2004" "volumen" => "31" "paginaInicial" => "51" "paginaFinal" => "55" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14739505" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Polypoid basal cell carcinoma on the nose tip" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M. Hirakawa" 1 => "Y. Ishikura" 2 => "T. Futatsuya" 3 => "R. Yamaguchi" 4 => "A. Shimizu" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Case Rep Dermatol Med" "fecha" => "2022" "volumen" => "2022" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A giant polypoid basal cell carcinoma of the lower extremity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "F. Handjani" 1 => "S. Shahbaz" 2 => "F. Sari-Aslani" 3 => "S. Aghaei" 4 => "A.A. Ali-Zadeh" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Iran Med" "fecha" => "2010" "volumen" => "13" "paginaInicial" => "153" "paginaFinal" => "155" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fibroepithelioma of pinkus revisited" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E.S. Haddock" 1 => "P.R. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s13555-016-0123-8" "Revista" => array:6 [ "tituloSerie" => "Dermatol Ther (Heidelb)" "fecha" => "2016" "volumen" => "6" "paginaInicial" => "347" "paginaFinal" => "362" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27329375" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/03650596/0000009900000005/v2_202409130645/S0365059624001016/v2_202409130645/en/main.assets" "Apartado" => array:4 [ "identificador" => "95691" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letter – Clinical" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03650596/0000009900000005/v2_202409130645/S0365059624001016/v2_202409130645/en/main.pdf?idApp=UINPBA00008Z&text.app=https://clinics.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059624001016?idApp=UINPBA00008Z" ]
| Ano/Mês | Html | Total | |
|---|---|---|---|
| 2024 Novembro | 19 | 9 | 28 |
| 2024 Outubro | 410 | 101 | 511 |
| 2024 Setembro | 401 | 127 | 528 |
| 2024 Agosto | 398 | 134 | 532 |
| 2024 Julho | 151 | 95 | 246 |
| 2024 Junho | 107 | 126 | 233 |
