Case Letter
Basaloid follicular hamartoma following Blaschko’s lines
Gabriela Martins de Queiroz
, Tayla Cristina Lopes, Maria Clara Dantas Valle Soares, Carlos Bruno Fernandes Lima
Autor para correspondência
Universidade Potiguar, Natal, RN, Brazil
Lido
4317
Vezesque se leu este artigo
1753
Total PDF
2564
Total HTML
Compartilhar estatÃsticas
array:22 [ "pii" => "S0365059622001866" "issn" => "03650596" "doi" => "10.1016/j.abd.2020.10.027" "estado" => "S300" "fechaPublicacion" => "2022-11-01" "aid" => "614" "copyrightAnyo" => "2022" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "pt" => array:17 [ "pii" => "S2666275222001977" "issn" => "26662752" "doi" => "10.1016/j.abdp.2022.09.010" "estado" => "S300" "fechaPublicacion" => "2022-11-01" "aid" => "614" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "pt" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta ‐ Caso clínico</span>" "titulo" => "Hamartoma folicular basaloide seguindo as linhas de Blaschko" "tienePdf" => "pt" "tieneTextoCompleto" => "pt" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "823" "paginaFinal" => "825" ] ] "contieneTextoCompleto" => array:1 [ "pt" => true ] "contienePdf" => array:1 [ "pt" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figura 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 989 "Ancho" => 1310 "Tamanyo" => 461104 ] ] "descripcion" => array:1 [ "pt" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Proliferações de células epitelioides basaloides com padrão cordonal e ilhotas em disposição radial (Hematoxilina & eosina, 200×).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Gabriela Martins de Queiroz, Tayla Cristina Lopes, Maria Clara Dantas Valle Soares, Carlos Bruno Fernandes Lima" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Gabriela Martins de" "apellidos" => "Queiroz" ] 1 => array:2 [ "nombre" => "Tayla Cristina" "apellidos" => "Lopes" ] 2 => array:2 [ "nombre" => "Maria Clara Dantas Valle" "apellidos" => "Soares" ] 3 => array:2 [ "nombre" => "Carlos Bruno Fernandes" "apellidos" => "Lima" ] ] ] ] ] "idiomaDefecto" => "pt" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S0365059622001866" "doi" => "10.1016/j.abd.2020.10.027" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622001866?idApp=UINPBA00008Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275222001977?idApp=UINPBA00008Z" "url" => "/26662752/0000009700000006/v4_202410140645/S2666275222001977/v4_202410140645/pt/main.assets" ] ] "itemSiguiente" => array:18 [ "pii" => "S0365059622001878" "issn" => "03650596" "doi" => "10.1016/j.abd.2020.12.020" "estado" => "S300" "fechaPublicacion" => "2022-11-01" "aid" => "615" "copyright" => "Sociedade Brasileira de Dermatologia" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "sco" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case Letter</span>" "titulo" => "Congenital infantile fibrosarcoma: a rare tumor dermatologists should know about" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "825" "paginaFinal" => "827" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1397 "Ancho" => 3341 "Tamanyo" => 434588 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Ulcerated and bleeding tumor mass. (B) After 13 weeks, significant increase in size (before the chemotherapy). (C) Tumor and ulcer reduction after adjuvant chemotherapy and before amputation.</p>" ] ] ] "autores" => array:4 [ 0 => array:2 [ "autoresLista" => "Luciana Baptista Pereira" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Luciana Baptista" "apellidos" => "Pereira" ] ] ] 1 => array:2 [ "autoresLista" => "João Renato Vianna Gontijo" "autores" => array:1 [ 0 => array:2 [ "nombre" => "João Renato Vianna" "apellidos" => "Gontijo" ] ] ] 2 => array:2 [ "autoresLista" => "Marcelo de Mattos Garcia" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Marcelo de Mattos" "apellidos" => "Garcia" ] ] ] 3 => array:2 [ "autoresLista" => "Karine Corrêa Fonseca" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Karine Corrêa" "apellidos" => "Fonseca" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "pt" => array:9 [ "pii" => "S2666275222001989" "doi" => "10.1016/j.abdp.2022.09.011" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275222001989?idApp=UINPBA00008Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622001878?idApp=UINPBA00008Z" "url" => "/03650596/0000009700000006/v2_202306261757/S0365059622001878/v2_202306261757/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0365059622001829" "issn" => "03650596" "doi" => "10.1016/j.abd.2021.10.009" "estado" => "S300" "fechaPublicacion" => "2022-11-01" "aid" => "610" "copyright" => "Sociedade Brasileira de Dermatologia" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Research Letter</span>" "titulo" => "Treatment of pediatric psoriasis with TNF-antagonists: a real-life single-center case series" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "819" "paginaFinal" => "822" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 3203 "Ancho" => 2508 "Tamanyo" => 287651 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Trends of mean PASI scores in all the study population (blue line), in adalimumab (red line) and in etanercept (green line) group at baseline and follow-ups. (B) Trends of mean BSA scores in all the study population (blue line), in adalimumab (red line) and in etanercept (green line) group at baseline and follow-ups.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Matteo Megna, Gabriella Fabbrocini, Lucia Gallo, Angelo Ruggiero, Elisa Camela, Sonia Sofía Ocampo-Garza, Eleonora Cinelli" "autores" => array:7 [ 0 => array:2 [ "nombre" => "Matteo" "apellidos" => "Megna" ] 1 => array:2 [ "nombre" => "Gabriella" "apellidos" => "Fabbrocini" ] 2 => array:2 [ "nombre" => "Lucia" "apellidos" => "Gallo" ] 3 => array:2 [ "nombre" => "Angelo" "apellidos" => "Ruggiero" ] 4 => array:2 [ "nombre" => "Elisa" "apellidos" => "Camela" ] 5 => array:2 [ "nombre" => "Sonia Sofía" "apellidos" => "Ocampo-Garza" ] 6 => array:2 [ "nombre" => "Eleonora" "apellidos" => "Cinelli" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "pt" => array:9 [ "pii" => "S266627522200193X" "doi" => "10.1016/j.abdp.2022.09.006" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S266627522200193X?idApp=UINPBA00008Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622001829?idApp=UINPBA00008Z" "url" => "/03650596/0000009700000006/v2_202306261757/S0365059622001829/v2_202306261757/en/main.assets" ] "en" => array:17 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case Letter</span>" "titulo" => "Basaloid follicular hamartoma following Blaschko’s lines" "tieneTextoCompleto" => true "saludo" => "Dear Editor," "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "823" "paginaFinal" => "825" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Gabriela Martins de Queiroz, Tayla Cristina Lopes, Maria Clara Dantas Valle Soares, Carlos Bruno Fernandes Lima" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Gabriela Martins de" "apellidos" => "Queiroz" "email" => array:1 [ 0 => "gabrielamartins96@yahoo.com.br" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Tayla Cristina" "apellidos" => "Lopes" ] 2 => array:2 [ "nombre" => "Maria Clara Dantas Valle" "apellidos" => "Soares" ] 3 => array:2 [ "nombre" => "Carlos Bruno Fernandes" "apellidos" => "Lima" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Universidade Potiguar, Natal, RN, Brazil" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2197 "Ancho" => 1675 "Tamanyo" => 349042 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hyperpigmented unilateral linear papular lesions; some are verrucous, on the face and neck..</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A six-year-old female patient presented with hyperchromic confluent papules on the trunk and face (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>), following the embryological lines, with well-defined contours, elastic on palpation, not pruritic or painful. Hypopigmented lesions appeared at 15 days of life on the facial region, and evolved in the first year of life to hyperchromic lesions, spreading to the cervical region and trunk. The lesions have been stable and asymptomatic since that time. The mother denied comorbidities or associated symptoms. The patient does not have any family history of similar lesions, neoplasms, or autoimmune diseases.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">On dermoscopy, the lesions were non-specific with a homogeneous brownish color and with structures similar to follicular crypts or openings (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Histopathological examination (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>) showed a well-circunscribed, basaloid, epithelioid cell proliferation in the superficial dermis, forming strands and islets in a radial pattern. Thus, a diagnosis of multiple basaloid follicular hamartomas was made.</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Basaloid follicular hamartoma (BFH) consists of the proliferation of multifocal basaloid cells, with frequent connection to the epidermis.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> BFH lesions may present as papules, nodules, or plaques, which may be skin-colored or hyperchromic. The cells are folliculocentric and restricted to the superficial dermis. The hair follicles are distorted, with branching strands from basaloid cells.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2,3</span></a> The present case showed a distribution of basaloid cells in strands and islets with a radial pattern in the superficial dermis, which clinically followed the embryological lines.</p><p id="par0025" class="elsevierStylePara elsevierViewall">The main differential diagnosis of BFH is basal cell carcinoma (BCC). Both consist histopathologically of basaloid strands of cells in a fibrous stroma, but the BCC is not folliculocentric and can be seen in the interfollicular dermis.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,3</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Acquired BFH can show a linear pattern, following the lines of Blaschko - occurring due to mosaicism - or in a generalized form - commonly associated with autoimmune diseases.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">In the case described herein, BFH clones were distributed along the Blaschko lines, representing ectodermal development patterns, which is a rare distribution. When a somatic mutation or chromosomal nondisjunction occurs during embryogenesis, affecting an epidermal progenitor cell, the affected offspring cells proliferate and migrate along the lines of Blaschko.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Currently, there is no standard treatment for BFH. Correct identification prevents patients from undergoing unnecessary surgery and also allows periodic monitoring to detect malignant transformations. Lesions that increase in size or change in appearance should be biopsied whenever detected. If associated with an autoimmune disease, treatment of the comorbidity may lead to the regression of the associated skin lesions.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">In summary, BFH is a rare type of benign skin tumor, with different presentations, which can be congenital or acquired. Its main differential diagnosis is basal cell carcinoma, and histopathology should be performed for differentiation. There is yet no standard treatment for this condition and, in most cases, it is not necessary.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Financial support</span><p id="par0050" class="elsevierStylePara elsevierViewall">None declared.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Authors’ contributions</span><p id="par0055" class="elsevierStylePara elsevierViewall">Gabriela Martins de Queiroz: Collection, analysis, and interpretation of data; design, planning, drafting and writing of the manuscript; critical review of the literature; critical review of the manuscript; approval of the final version of the manuscript.</p><p id="par0060" class="elsevierStylePara elsevierViewall">Tayla Cristina Lopes: Collection, analysis, and interpretation of data; design, planning, drafting and writing of the manuscript; critical review of the literature; critical review of the manuscript; approval of the final version of the manuscript.</p><p id="par0065" class="elsevierStylePara elsevierViewall">Maria Clara Dantas Valle Soares: Analysis and interpretation of data; drafting and writing of the manuscript; critical review of the literature; critical review of the manuscript; approval of the final version of the manuscript.</p><p id="par0070" class="elsevierStylePara elsevierViewall">Carlos Bruno Fernandes Lima: Analysis and interpretation of data, design and planning of the manuscript; critical review of the literature; critical review of the manuscript; approval of the final version of the manuscript.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflicts of interest</span><p id="par0075" class="elsevierStylePara elsevierViewall">None declared.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:4 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Financial support" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Authors’ contributions" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Conflicts of interest" ] 3 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2020-08-28" "fechaAceptado" => "2020-10-23" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "⋆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Study conducted at the Hospital Infantil Varela Santiago, Natal, RN, Brazil.</p>" ] ] "multimedia" => array:3 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2197 "Ancho" => 1675 "Tamanyo" => 349042 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hyperpigmented unilateral linear papular lesions; some are verrucous, on the face and neck..</p>" ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2230 "Ancho" => 1675 "Tamanyo" => 389336 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Dermoscopy showing brownish, crypt-like structures.</p>" ] ] 2 => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1628 "Ancho" => 2175 "Tamanyo" => 960831 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Proliferation of basaloid epithelioid cells in strands and islets showing a radial pattern (Hematoxylin & eosin, ×200).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tumours of the skin appendages" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "E. Calonje" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:6 [ "editores" => "TBurns, SBreathnach, NCox, CGriffiths" "titulo" => "Rook’s Textbook of Dermatology" "paginaInicial" => "53.11" "paginaFinal" => "53.12" "edicion" => "8th ed." "serieFecha" => "2010" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Generalized basaloid follicular hamartoma syndrome: a case report and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "P. Gumaste" 1 => "A. Ortiz" 2 => "A. Patel" 3 => "J. Baron" 4 => "R. Harris" 5 => "R. Barr" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "2015" "volumen" => "37" "paginaInicial" => "37" "paginaFinal" => "40" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Basaloid follicular hamartoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "O Mills" 1 => "B Thomas" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.5858/2008-0620-RS.1" "Revista" => array:6 [ "tituloSerie" => "Arch Pathol Lab Med" "fecha" => "2010" "volumen" => "134" "paginaInicial" => "1215" "paginaFinal" => "1219" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20670146" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous mosaicisms: concepts, patterns and classifications" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.S. Kouzak" 1 => "M.S. Mendes" 2 => "I.M. Costa" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1590/abd1806-4841.20132015" "Revista" => array:6 [ "tituloSerie" => "An Bras Dermatol" "fecha" => "2013" "volumen" => "88" "paginaInicial" => "507" "paginaFinal" => "517" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24068120" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/03650596/0000009700000006/v2_202306261757/S0365059622001866/v2_202306261757/en/main.assets" "Apartado" => array:4 [ "identificador" => "82769" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case Letter" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03650596/0000009700000006/v2_202306261757/S0365059622001866/v2_202306261757/en/main.pdf?idApp=UINPBA00008Z&text.app=https://clinics.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622001866?idApp=UINPBA00008Z" ]
| Ano/Mês | Html | Total | |
|---|---|---|---|
| 2024 Novembro | 24 | 8 | 32 |
| 2024 Outubro | 134 | 61 | 195 |
| 2024 Setembro | 157 | 96 | 253 |
| 2024 Agosto | 199 | 114 | 313 |
| 2024 Julho | 153 | 109 | 262 |
| 2024 Junho | 115 | 100 | 215 |
| 2024 Maio | 97 | 79 | 176 |
| 2024 Abril | 111 | 100 | 211 |
| 2024 Março | 96 | 70 | 166 |
| 2024 Fevereiro | 114 | 87 | 201 |
| 2024 Janeiro | 78 | 69 | 147 |
| 2023 Dezembro | 73 | 67 | 140 |
| 2023 Novembro | 124 | 87 | 211 |
| 2023 Outubro | 104 | 73 | 177 |
| 2023 Setembro | 115 | 77 | 192 |
| 2023 Agosto | 99 | 33 | 132 |
| 2023 Julho | 96 | 37 | 133 |
| 2023 Junho | 76 | 61 | 137 |
| 2023 Maio | 62 | 24 | 86 |
| 2023 Abril | 40 | 16 | 56 |
| 2023 Março | 61 | 42 | 103 |
| 2023 Fevereiro | 49 | 42 | 91 |
| 2023 Janeiro | 69 | 52 | 121 |
| 2022 Dezembro | 79 | 49 | 128 |
| 2022 Novembro | 114 | 95 | 209 |
| 2022 Outubro | 101 | 80 | 181 |
| 2022 Setembro | 24 | 25 | 49 |
Mostrar tudo
