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(A) Máculas e placas violáceas na face lateral direita do pescoço aos 2 anos de idade; primeira apresentação de AT quando da descontinuação de aspirina e ticlopidina. (B) Regressão parcial após reintrodução de aspirina em monoterapia.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Lula María Nieto‐Benito, Jorge Huerta‐Aragonés, Verónica Parra‐Blanco, Minia Campos‐Domínguez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Lula María" "apellidos" => "Nieto‐Benito" ] 1 => array:2 [ "nombre" => "Jorge" "apellidos" => "Huerta‐Aragonés" ] 2 => array:2 [ "nombre" => "Verónica" "apellidos" => "Parra‐Blanco" ] 3 => array:2 [ "nombre" => "Minia" "apellidos" => "Campos‐Domínguez" ] ] ] ] ] "idiomaDefecto" => "pt" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S036505962200318X" "doi" => "10.1016/j.abd.2021.07.010" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S036505962200318X?idApp=UINPBA00008Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S266627522300022X?idApp=UINPBA00008Z" "url" => "/26662752/0000009800000003/v3_202305121556/S266627522300022X/v3_202305121556/pt/main.assets" ] ] "itemSiguiente" => array:17 [ "pii" => "S036505962300003X" "issn" => "03650596" "doi" => "10.1016/j.abd.2021.06.011" "estado" => "S300" "fechaPublicacion" => "2023-05-01" "aid" => "702" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter - Clinical</span>" "titulo" => "Langerhans cell histiocytosis: a rare case of the multisystemic form in an infant" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "394" "paginaFinal" => "395" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 978 "Ancho" => 1675 "Tamanyo" => 270767 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Positive immunohistochemistry for CD1a.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Thaís Oliveira Utiyama, Maria Laura Malzoni, Thalita Gabrieli Sanches Vasques, Cassiano Tamura Vieira Gomes" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Thaís Oliveira" "apellidos" => "Utiyama" ] 1 => array:2 [ "nombre" => "Maria Laura" "apellidos" => "Malzoni" ] 2 => array:2 [ "nombre" => "Thalita Gabrieli Sanches" "apellidos" => "Vasques" ] 3 => array:2 [ "nombre" => "Cassiano Tamura Vieira" "apellidos" => "Gomes" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "pt" => array:9 [ "pii" => "S2666275223000279" "doi" => "10.1016/j.abdp.2023.01.010" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "pt" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275223000279?idApp=UINPBA00008Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S036505962300003X?idApp=UINPBA00008Z" "url" => "/03650596/0000009800000003/v3_202305121633/S036505962300003X/v3_202305121633/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0365059622003142" "issn" => "03650596" "doi" => "10.1016/j.abd.2021.01.013" "estado" => "S300" "fechaPublicacion" => "2023-05-01" "aid" => "693" "copyright" => "Sociedade Brasileira de Dermatologia" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:9 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter - Clinical</span>" "titulo" => "Elevation of transaminases after MMP® session with methotrexate for alopecia areata treatment – how much do we know about the risks of systemic absorption of the technique?" 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(A) Vascular proliferation in the papillary and medium dermis; nodules were composed of tufted vascular vessels lined with endothelial cells. These endothelial cells were fVIII, CD31 and CD34 positive (podoplanin negative). (B) These nodules were surrounded at the periphery by semilunar vascular spaces (podoplanin positive).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">kaposiform hemangioendothelioma (KHE) and tufted angioma (TA) are very rare vascular tumors<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a>; however, they are associated with important morbidity and mortality.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Their clinical presentation is very heterogeneous and, especially in KHE, potential associated complications add difficulties to the management.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,3</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">A 28-day-old male infant, born at 33 weeks of gestation with a diagnosis of nonimmune <span class="elsevierStyleItalic">hydrops fetalis</span>, presented with an asymmetry of the right face, neck, and thorax after partial resolution of the generalized edema (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). On physical examination, an erythematous-bluish-purpuric vascular-like tumor extending from the right parotid and cervical area to the ipsilateral chest was observed. A diagnosis of KHE complicated with the kasabach-merritt phenomenon (KMP) was made through laboratory test results and magnetic resonance imaging (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). Intravenous treatment with vincristine, aspirin, ticlopidine and prednisone lead to the reduction in the size of the tumor and the improvement of the clinical condition.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Aspirin and ticlopidine were maintained without any recurrence, symptomatic, or laboratory abnormalities. However, several months after discontinuation due to vaccination, dark-red and violaceous macules and plaques started to develop in the same location as prior HEK (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Histopathological study from these lesions showed a vascular, well-defined nodular proliferation located in the papillary and medium dermis with a “cannonball” appearance. These nodules were formed by closely packed small vascular vessels lined with endothelial cells and pericytes; vascular spaces were present and some of them were located at the periphery, surrounding the nodules, with a semilunar/crescent-shaped morphology (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>). No mitotic figures, atypical cells or changes at the epidermis were present. An immunohistochemistry panel was also performed, and a diagnosis of TA was made. Aspirin was then reintroduced with clinical control and partial clearance (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). New flares at the same location have been experienced when discontinuing aspirin, with complete control after reintroduction.</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">HEK and TA are vascular tumors with aggressive and intermediate behavior, respectively.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1–3</span></a> Regarding complications, KMP is the most severe. Both entities share clinical, histopathological, and molecular features (GNA14 mutations); therefore, it has been suggested to be two polar ends of the same spectrum.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> TA usually presents during infancy or early childhood with non-aggressive behavior.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2,4</span></a> Purpuric, dark red or brownish macules, papules and plaques are characteristic, although a deep nodular component or extension to the trunk and elbow can be observed.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a> The presence of dermal tufts of vessels in a cannonball pattern is pathognomonic (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>).<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Although recommended, histopathological studies can be omitted in life-threatening cases.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4,5</span></a> Concerning treatment, non-complicated, early and asymptomatic TA cases may not benefit from treatment.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,5</span></a> Systemic corticosteroids, intravenous vincristine, mTOR inhibitors, α-interferon and antiplatelet drugs have been used successfully in the treatment of KHE/TA.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> VAT (Vincristin, Aspirin and Ticlopidine) therapy, as presented, has demonstrated its efficacy in cases of KHE/TA associated to KMP.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Sirolimus, an mTOR inhibitor, has demonstrated great results in complicated, non-complicated, and refractory cases of KHE/TA.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2,5</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">In conclusion, the authors present a case of neonatal KEH complicated with KMP, successfully treated with VAT therapy with posterior development of TA. TA relapses were experienced when discontinuing aspirin, with complete control after reintroduction in monotherapy.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Financial support</span><p id="par0035" class="elsevierStylePara elsevierViewall">None declared.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Authors’ contributions</span><p id="par0040" class="elsevierStylePara elsevierViewall">Lula María Nieto-Benito and Minia Campos-Domínguez conceived and designed the study, collected the data, and wrote and reviewed the paper. Jorge Huerta-Aragonés and Verónica Parra-Blanco conceived the study and reviewed the paper.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflicts of interest</span><p id="par0045" class="elsevierStylePara elsevierViewall">None declared.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:4 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Financial support" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Authors’ contributions" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Conflicts of interest" ] 3 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2021-05-26" "fechaAceptado" => "2021-07-04" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Study conducted at the Department of Dermatology and Venereology, Hospital General Universitario Gregorio Marañón, Universidad Complutense, Madrid, Spain.</p>" ] ] "multimedia" => array:3 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1205 "Ancho" => 2925 "Tamanyo" => 240396 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical and radiological images of kaposiform hemangioendothelioma (KHE). (A) Clinical image at presentation: vascular-like lesion located at his right cervical area and chest. (B) Radiological image of a vascular tumor compatible with HEK with deep endocervical extension.</p>" ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1812 "Ancho" => 2508 "Tamanyo" => 309439 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Clinical images of tufted angioma (TA) lesions. (A) Violaceous macules and plaques on the right lateral aspect of the neck at the age of two; first presentation of TA when discontinuation of aspirin and ticlopidine. (B) Partial clearance after reintroduction of aspirin in monotherapy.</p>" ] ] 2 => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1369 "Ancho" => 2925 "Tamanyo" => 672768 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Histopathological features of tufted angioma (TA). (A) Vascular proliferation in the papillary and medium dermis; nodules were composed of tufted vascular vessels lined with endothelial cells. These endothelial cells were fVIII, CD31 and CD34 positive (podoplanin negative). (B) These nodules were surrounded at the periphery by semilunar vascular spaces (podoplanin positive).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Kaposiform hemangioendothelioma: current knowledge and future perspectives" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "Y. Ji" 1 => "S. Chen" 2 => "K. Yang" 3 => "C. Xia" 4 => "L. Li" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1186/s13023-020-1320-1" "Revista" => array:5 [ "tituloSerie" => "Orphanet J Rare Dis." "fecha" => "2020" "volumen" => "15" "paginaInicial" => "39" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32014025" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The clinical spectrum of Kaposiform hemagioendothelioma and tufted angioma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S. Croteau" 1 => "D. Gupta" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.12788/j.sder.2016.048" "Revista" => array:6 [ "tituloSerie" => "Semin Cutan Med Surg." "fecha" => "2016" "volumen" => "35" "paginaInicial" => "147" "paginaFinal" => "152" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27607323" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Kaposiform Hemangioendothelioma presenting as hydrops fetalis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E. Sobrino-Fernández" 1 => "M. Campos-Domínguez" 2 => "R. Gregorio-Hernández" 3 => "J. Huerta-Aragonés" 4 => "C. Beléndez-Bieler" 5 => "A. Lancharro-Zapata" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Pediatric Dermatol." "fecha" => "2017" "volumen" => "34" "paginaInicial" => "e128" "paginaFinal" => "9" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Vascular tumors in infants: case report and review of clinical, histopathologic and immunohistochemical characteristics on infantile hemangioma, pyogenic granuloma, no involuting congenital hemangioma, tufted angioma and kaposiform hemangioendothelioma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E.F. Johnson" 1 => "D.M. Davis" 2 => "M.M. Tollefson" 3 => "K. Fritchie" 4 => "L.E. Gibson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DAD.0000000000000983" "Revista" => array:6 [ "tituloSerie" => "Am J Dermatopathol." "fecha" => "2018" "volumen" => "40" "paginaInicial" => "231" "paginaFinal" => "239" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29561329" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low dose sirolimus treatment for refractory tufted angioma and congenital kaposiform hemangioendothelioma, both Kasabach-Merritt phenomenon" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L.G. Mariani" 1 => "I.R. Schmitt" 2 => "C.D. Garcia" 3 => "A.E. Kiszewski" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Pediatr Blood Cancer." "fecha" => "2019" "volumen" => "66" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/03650596/0000009800000003/v3_202305121633/S036505962200318X/v3_202305121633/en/main.assets" "Apartado" => array:4 [ "identificador" => "95691" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letter – Clinical" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03650596/0000009800000003/v3_202305121633/S036505962200318X/v3_202305121633/en/main.pdf?idApp=UINPBA00008Z&text.app=https://clinics.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S036505962200318X?idApp=UINPBA00008Z" ]
Year/Month | Html | Total | |
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