array:24 [
  "pii" => "S0365059622000435"
  "issn" => "03650596"
  "doi" => "10.1016/j.abd.2021.09.005"
  "estado" => "S300"
  "fechaPublicacion" => "2022-05-01"
  "aid" => "537"
  "copyright" => "Sociedade Brasileira de Dermatologia"
  "copyrightAnyo" => "2022"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by/4.0/"
  "subdocumento" => "crp"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "pt" => array:19 [
      "pii" => "S2666275222000595"
      "issn" => "26662752"
      "doi" => "10.1016/j.abdp.2022.03.018"
      "estado" => "S300"
      "fechaPublicacion" => "2022-05-01"
      "aid" => "537"
      "copyright" => "Sociedade Brasileira de Dermatologia"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by/4.0/"
      "subdocumento" => "crp"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:1 [
        "total" => 0
      ]
      "pt" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Qual o seu diagn&#243;stico&#63;</span>"
        "titulo" => "Caso para diagn&#243;stico&#46; Eros&#227;o dolorosa perianal e intergl&#250;tea com bordas pustulosas circinadas"
        "tienePdf" => "pt"
        "tieneTextoCompleto" => "pt"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "376"
            "paginaFinal" => "378"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "pt" => true
        ]
        "contienePdf" => array:1 [
          "pt" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0010"
            "etiqueta" => "Figura 2"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr2.jpeg"
                "Alto" => 1606
                "Ancho" => 1508
                "Tamanyo" => 721987
              ]
            ]
            "descripcion" => array:1 [
              "pt" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Microscopia &#243;ptica com fenda e microabscesso de polimorfonucleares &#40;setas&#41; &#40;Hematoxilina &#38; eosina&#44; 150<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>&#41;&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Hiram Larangeira de Almeida Jr, Ant&#244;nia Larangeira de Almeida, Pedro Henrique Evangelista Martinez, Ana Let&#237;cia Boff"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "Hiram Larangeira de"
                "apellidos" => "Almeida Jr"
              ]
              1 => array:2 [
                "nombre" => "Ant&#244;nia Larangeira de"
                "apellidos" => "Almeida"
              ]
              2 => array:2 [
                "nombre" => "Pedro Henrique Evangelista"
                "apellidos" => "Martinez"
              ]
              3 => array:2 [
                "nombre" => "Ana Let&#237;cia"
                "apellidos" => "Boff"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "pt"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S0365059622000435"
          "doi" => "10.1016/j.abd.2021.09.005"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622000435?idApp=UINPBA00008Z"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275222000595?idApp=UINPBA00008Z"
      "url" => "/26662752/0000009700000003/v1_202206050551/S2666275222000595/v1_202206050551/pt/main.assets"
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0365059622000393"
    "issn" => "03650596"
    "doi" => "10.1016/j.abd.2020.12.012"
    "estado" => "S300"
    "fechaPublicacion" => "2022-05-01"
    "aid" => "533"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by/4.0/"
    "subdocumento" => "sco"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Research Letter</span>"
      "titulo" => "Allergic contact dermatitis to corticosteroids&#58; experience of a referral clinic from 2014 to 2018"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "379"
          "paginaFinal" => "382"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 2164
              "Ancho" => 1340
              "Tamanyo" => 341943
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Eczema on the lower limb due to allergic contact dermatitis to corticosteroid&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Mariana de Figueiredo Silva Hafner, Amanda Ivanchuk Lopes, Nathalie Mie Suzuki, Rosana Lazzarini"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Mariana de Figueiredo Silva"
              "apellidos" => "Hafner"
            ]
            1 => array:2 [
              "nombre" => "Amanda Ivanchuk"
              "apellidos" => "Lopes"
            ]
            2 => array:2 [
              "nombre" => "Nathalie Mie"
              "apellidos" => "Suzuki"
            ]
            3 => array:2 [
              "nombre" => "Rosana"
              "apellidos" => "Lazzarini"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "pt" => array:9 [
        "pii" => "S2666275222000522"
        "doi" => "10.1016/j.abdp.2022.03.011"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "pt"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275222000522?idApp=UINPBA00008Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622000393?idApp=UINPBA00008Z"
    "url" => "/03650596/0000009700000003/v1_202205170747/S0365059622000393/v1_202205170747/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S0365059622000290"
    "issn" => "03650596"
    "doi" => "10.1016/j.abd.2021.04.015"
    "estado" => "S300"
    "fechaPublicacion" => "2022-05-01"
    "aid" => "523"
    "copyright" => "Sociedade Brasileira de Dermatologia"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by/4.0/"
    "subdocumento" => "crp"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Images in Dermatology</span>"
      "titulo" => "Isolated hair loss on the eyebrow&#58; five cases with trichoscopic features"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "372"
          "paginaFinal" => "375"
        ]
      ]
      "contieneResumen" => array:1 [
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0025"
          "etiqueta" => "Figure 5"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr5.jpeg"
              "Alto" => 606
              "Ancho" => 1304
              "Tamanyo" => 130786
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0025"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Broken hair &#40;red arrow&#41;&#44; comma hair &#40;red circle&#41;&#46; &#40;B&#41;&#44; Tulip hair &#40;green circle&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "G&#252;ldehan At&#305;&#351;, Ay&#351;enur &#350;am Sar&#305;, Pembeg&#252;l G&#252;ne&#351;, Cansu S&#246;nmez"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "G&#252;ldehan"
              "apellidos" => "At&#305;&#351;"
            ]
            1 => array:2 [
              "nombre" => "Ay&#351;enur &#350;am"
              "apellidos" => "Sar&#305;"
            ]
            2 => array:2 [
              "nombre" => "Pembeg&#252;l"
              "apellidos" => "G&#252;ne&#351;"
            ]
            3 => array:2 [
              "nombre" => "Cansu"
              "apellidos" => "S&#246;nmez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "pt" => array:9 [
        "pii" => "S266627522200042X"
        "doi" => "10.1016/j.abdp.2022.03.001"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "pt"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S266627522200042X?idApp=UINPBA00008Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622000290?idApp=UINPBA00008Z"
    "url" => "/03650596/0000009700000003/v1_202205170747/S0365059622000290/v1_202205170747/en/main.assets"
  ]
  "en" => array:19 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">What is your diagnosis&#63;</span>"
    "titulo" => "Case for diagnosis&#46; Radiotherapy-induced pemphigus vegetans"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "376"
        "paginaFinal" => "378"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Hiram Larangeira de Almeida Jr, Ant&#244;nia Larangeira de Almeida, Pedro Henrique Evangelista Martinez, Ana Let&#237;cia Boff"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "Hiram Larangeira de"
            "apellidos" => "Almeida Jr"
            "email" => array:1 [
              0 => "hiramalmeidajr@hotmail.com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Ant&#244;nia Larangeira de"
            "apellidos" => "Almeida"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Pedro Henrique Evangelista"
            "apellidos" => "Martinez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Ana Let&#237;cia"
            "apellidos" => "Boff"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "P&#243;s-Gradua&#231;&#227;o em Sa&#250;de e Comportamento&#44; Universidade Cat&#243;lica de Pelotas&#44; Departamento de Dermatologia&#44; Universidade Federal de Pelotas&#44; Pelotas&#44; RS&#44; Brazil"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Liga de Dermatologia&#44; Universidade Federal de Pelotas&#44; Pelotas&#44; RS&#44; Brazil"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Laborat&#243;rio Dermapat and Santa Casa de Miseric&#243;rdia de Porto Alegre&#44; Porto Alegre&#44; RS&#44; Brazil"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 611
            "Ancho" => 905
            "Tamanyo" => 70089
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Initial clinical aspect with perianal and intergluteal erosion with circinate pustular edges and some isolated pustules&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect1005">Case report</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 73-year-old male patient developed a vegetating lesion in the anal canal nine months ago&#59; the histopathology showed a non-keratinizing poorly differentiated squamous cell carcinoma&#46; He was treated with two cycles of 5-fluorouracil and cisplatin and concomitant radiotherapy &#40;6&#8201;MeV linear photon accelerator&#44; total dose of 54&#8201;Gy&#41;&#44; with complete remission&#46; The control colonoscopy and endoscopy after six months of treatment were normal&#46; Forty-five days before coming to the clinic again&#44; he had a painful perianal and intergluteal erosion with circinate pustular borders and some isolated pustules&#44; with surrounding erythema &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; He was hospitalized and received systemic antibiotics &#40;ceftriaxone and clindamycin&#41; and famciclovir&#46; A computed tomography on admission ruled out tumor recurrence&#44; showing a normal anal canal&#46; An incisional biopsy was performed&#44; which showed pseudoepitheliomatous hyperplasia with microabscesses of inflammatory cells &#40;neutrophils and eosinophils&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; In some microscopic fields&#44; clefts with isolated keratinocytes next to microabscesses were observed &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">What is your diagnosis&#63;</span><p id="par0010" class="elsevierStylePara elsevierViewall"><ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">a&#41;</span><p id="par0015" class="elsevierStylePara elsevierViewall">Ulcerated herpes simplex associated with immunosuppression</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">b&#41;</span><p id="par0020" class="elsevierStylePara elsevierViewall">Ulcerated radiodermatitis</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">c&#41;</span><p id="par0025" class="elsevierStylePara elsevierViewall">Pemphigus vegetans</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">d&#41;</span><p id="par0030" class="elsevierStylePara elsevierViewall">Tinea associated with immunosuppression</p></li></ul></p><p id="par0035" class="elsevierStylePara elsevierViewall">The histopathological findings were suggestive of pemphigus vegetans&#44; which may present with acantholytic clefts associated with polymorphonuclear microabscesses&#44;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> unlike classic pemphigus vulgaris in which the cleavage is accompanied by little inflammation&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">There was no therapeutic response to systemic antibiotics and antivirals initiated before the results of the investigation&#44; and there was significant regression with oral prednisone &#40;40&#8201;mg&#41; and topical betamethasone&#46; After seven days&#44; the pustular border disappeared&#44; and there was total symptom regression&#44; with the appearance of some hyperkeratotic and verrucous central areas &#40;<a class="elsevierStyleCrossRef" href="#fig0020">Fig&#46; 4</a>&#41;&#46; Later&#44; the result of indirect immunofluorescence was positive for IgG&#44; with an intercellular pattern&#44; 1&#58;80 titer&#46;</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">There are several reports of radiotherapy-induced pemphigus vulgaris&#44; but not of the vegetans variant&#46; Reported cases are restricted to the irradiated area&#44;<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2&#44;3</span></a> &#40;similarly to the case described here&#41; or generalized&#46;<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#44;5</span></a> There have also been reports of pemphigus foliaceus induction&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">The mechanism of induction of autoimmune acantholytic diseases by radiotherapy must be complex&#46; One possibility is the antigenic alteration by radiation&#59;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> another possibility would be the alteration of the immune response&#46; Corroborating the hypothesis of antigenic alteration&#44; there are reports of laboratory investigation with immunoblotting demonstrating antibodies against antigens other than desmogleins&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">This case demonstrates the possibility that pemphigus vegetans lesions may occur locally on a previously irradiated area&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect1015">Financial support</span><p id="par0060" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Authors&#8217; contributions</span><p id="par0065" class="elsevierStylePara elsevierViewall">Hiram Larangeira de Almeida Jr&#46;&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis&#44; and interpretation of data&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Ant&#244;nia Larangeira de Almeida&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis&#44; and interpretation of data&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Pedro Henrique Evangelista Martinez&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis&#44; and interpretation of data&#59; intellectual participation in propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Ana Let&#237;cia Boff&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis&#44; and interpretation of data&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conflicts of interest</span><p id="par0085" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:8 [
        0 => array:3 [
          "identificador" => "xres1711211"
          "titulo" => "Abstract"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0005"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec1513461"
          "titulo" => "Keywords"
        ]
        2 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Case report"
        ]
        3 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "What is your diagnosis&#63;"
        ]
        4 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Financial support"
        ]
        5 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Authors&#8217; contributions"
        ]
        6 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Conflicts of interest"
        ]
        7 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2021-07-16"
    "fechaAceptado" => "2021-09-13"
    "PalabrasClave" => array:1 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1513461"
          "palabras" => array:2 [
            0 => "Radiotherapy"
            1 => "Pemphigus vegetans"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:1 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar1030" class="elsevierStyleSimplePara elsevierViewall">A 73-year-old male patient developed a poorly differentiated squamous cell carcinoma in the anal canal nine months ago&#46; He was treated with two cycles of 5-fluorouracil and cisplatin and concomitant radiotherapy &#40;6&#8201;MeV linear photon accelerator&#44; total dose of 54&#8201;Gy&#41;&#44; with complete remission&#46; Since forty-five days he presentes a painful perianal and intergluteal erosion with circinate pustular borders&#46; Light microscopy showed pseudoepitheliomatous hyperplasia of the epidermis with microabscesses of inflammatory cells &#40;neutrophils and eosinophils&#41; and acantholytic keratinocytes &#46; Indirect immunofluorescence was positive for IgG&#44; with an intercellular pattern&#44; 1&#58;80 titer&#46; The diagnosis of radiotherapy-induced pemphigus vegetans was established and there was significant regression with oral prednisone &#40;40 mg&#41; and topical betamethasone&#46;</p></span>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Study conducted at the Liga de Dermatologia da Universidade Federal de Pelotas&#44; Pelotas&#44; RS&#44; Brazil&#46;</p>"
      ]
    ]
    "multimedia" => array:4 [
      0 => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 611
            "Ancho" => 905
            "Tamanyo" => 70089
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Initial clinical aspect with perianal and intergluteal erosion with circinate pustular edges and some isolated pustules&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1606
            "Ancho" => 1508
            "Tamanyo" => 721987
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0010"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Light microscopy showing clefts and polymorphonuclear microabscess &#40;Hematoxylin &#38; eosin&#44; &#215;150&#41;&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 788
            "Ancho" => 905
            "Tamanyo" => 251024
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0015"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Light microscopy detailing the clefts and polymorphonuclear microabscess with suprabasal cleavage &#40;arrows&#41; and acantholytic keratinocytes &#40;arrowheads&#41;&#59; &#40;Hematoxylin &#38; eosin&#44; &#215;400&#41;&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "fig0020"
        "etiqueta" => "Figure 4"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr4.jpeg"
            "Alto" => 669
            "Ancho" => 905
            "Tamanyo" => 117476
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0020"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Clinical aspect with significant improvement after seven days of treatment&#44; without the circinate pustular borders and mild verrucosity in the center&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:7 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pemphigus vegetans associated with verrucous lesions&#58; expanding a phenotype"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "H&#46;L&#46; Almeida Jr"
                            1 => "M&#46;G&#46;P&#46; Neugebauer"
                            2 => "I&#46;M&#46; Guarenti"
                            3 => "V&#46; Aoki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Clinics &#40;S&#227;o Paulo&#41;"
                        "fecha" => "2006"
                        "volumen" => "61"
                        "paginaInicial" => "279"
                        "paginaFinal" => "282"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#91;Radiotherapy-induced pemphigus&#93;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;P&#46; Correia"
                            1 => "D&#46; Santos"
                            2 => "M&#46; Jorge"
                            3 => "S&#46; Coutinho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Med Port"
                        "fecha" => "1998"
                        "volumen" => "11"
                        "paginaInicial" => "581"
                        "paginaFinal" => "583"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9773540"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiation-induced pemphigus vulgaris of the breast"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "R&#46; Vigna-Taglianti"
                            1 => "E&#46;G&#46; Russi"
                            2 => "N&#46; Denaro"
                            3 => "G&#46; Numico"
                            4 => "R&#46; Brizio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer&#47;Radioth&#233;r"
                        "fecha" => "2011"
                        "volumen" => "15"
                        "paginaInicial" => "334"
                        "paginaFinal" => "337"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#91;Radiotherapy-induced pemphigus&#58; a case report&#93;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Mseddi"
                            1 => "S&#46; Bouassida"
                            2 => "M&#46; Khemakhem"
                            3 => "S&#46; Marrekchi"
                            4 => "W&#46; Abdelmaksoud"
                            5 => "H&#46; Hadjtaieb"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.canrad.2004.10.007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer Radiother"
                        "fecha" => "2005"
                        "volumen" => "9"
                        "paginaInicial" => "96"
                        "paginaFinal" => "98"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15820437"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiation-associated pemphigus vulgaris in a patient with preceding malignancy&#58; treatment with rituximab as a valuable option"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "F&#46; Schauer"
                            1 => "N&#46; Ishii"
                            2 => "M&#46; Mockenhaupt"
                            3 => "L&#46; Bruckner-Tuderman"
                            4 => "T&#46; Hashimoto"
                            5 => "D&#46; Kiritsi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3389/fimmu.2019.03116"
                      "Revista" => array:5 [
                        "tituloSerie" => "Front Immunol"
                        "fecha" => "2020"
                        "volumen" => "10"
                        "paginaInicial" => "3116"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32038636"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiotherapy-induced Pemphigus Foliaceous&#58; a rare adverse effect of breast cancer therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "P&#46;R&#46; Criado"
                            1 => "C&#46;D&#46;A&#46; Machado Filho"
                            2 => "R&#46;F&#46;J&#46; Criado"
                            3 => "I&#46;C&#46;R&#46; Etcheverria"
                            4 => "L&#46;M&#46; Umeda"
                            5 => "G&#46; Landman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2018"
                        "volumen" => "57"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiotherapy-induced pemphigus vulgaris with autoantibodies targeting a 110 kDa epidermal antigen"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "T&#46; Badri"
                            1 => "H&#46; Hammami"
                            2 => "A&#46; Lachkham"
                            3 => "R&#46; Benmously-Mlika"
                            4 => "I&#46; Mokhtar"
                            5 => "S&#46; Fenniche"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-4632.2011.04889.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2011"
                        "volumen" => "50"
                        "paginaInicial" => "1475"
                        "paginaFinal" => "1479"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22097992"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/03650596/0000009700000003/v1_202205170747/S0365059622000435/v1_202205170747/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "80633"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "What is your Diagnosis&#63;"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03650596/0000009700000003/v1_202205170747/S0365059622000435/v1_202205170747/en/main.pdf?idApp=UINPBA00008Z&text.app=https://clinics.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622000435?idApp=UINPBA00008Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

What is your diagnosis?
Case for diagnosis. Radiotherapy-induced pemphigus vegetans
Hiram Larangeira de Almeida Jra,
Corresponding author
hiramalmeidajr@hotmail.com

Corresponding author.
, Antônia Larangeira de Almeidab, Pedro Henrique Evangelista Martinezb, Ana Letícia Boffc
a Pós-Graduação em Saúde e Comportamento, Universidade Católica de Pelotas, Departamento de Dermatologia, Universidade Federal de Pelotas, Pelotas, RS, Brazil
b Liga de Dermatologia, Universidade Federal de Pelotas, Pelotas, RS, Brazil
c Laboratório Dermapat and Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, RS, Brazil
Read
4813
Times
was read the article
1945
Total PDF
2868
Total HTML
Share statistics
 array:24 [
  "pii" => "S0365059622000435"
  "issn" => "03650596"
  "doi" => "10.1016/j.abd.2021.09.005"
  "estado" => "S300"
  "fechaPublicacion" => "2022-05-01"
  "aid" => "537"
  "copyright" => "Sociedade Brasileira de Dermatologia"
  "copyrightAnyo" => "2022"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by/4.0/"
  "subdocumento" => "crp"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "pt" => array:19 [
      "pii" => "S2666275222000595"
      "issn" => "26662752"
      "doi" => "10.1016/j.abdp.2022.03.018"
      "estado" => "S300"
      "fechaPublicacion" => "2022-05-01"
      "aid" => "537"
      "copyright" => "Sociedade Brasileira de Dermatologia"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by/4.0/"
      "subdocumento" => "crp"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:1 [
        "total" => 0
      ]
      "pt" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Qual o seu diagn&#243;stico&#63;</span>"
        "titulo" => "Caso para diagn&#243;stico&#46; Eros&#227;o dolorosa perianal e intergl&#250;tea com bordas pustulosas circinadas"
        "tienePdf" => "pt"
        "tieneTextoCompleto" => "pt"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "376"
            "paginaFinal" => "378"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "pt" => true
        ]
        "contienePdf" => array:1 [
          "pt" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0010"
            "etiqueta" => "Figura 2"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr2.jpeg"
                "Alto" => 1606
                "Ancho" => 1508
                "Tamanyo" => 721987
              ]
            ]
            "descripcion" => array:1 [
              "pt" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Microscopia &#243;ptica com fenda e microabscesso de polimorfonucleares &#40;setas&#41; &#40;Hematoxilina &#38; eosina&#44; 150<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>&#41;&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Hiram Larangeira de Almeida Jr, Ant&#244;nia Larangeira de Almeida, Pedro Henrique Evangelista Martinez, Ana Let&#237;cia Boff"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "Hiram Larangeira de"
                "apellidos" => "Almeida Jr"
              ]
              1 => array:2 [
                "nombre" => "Ant&#244;nia Larangeira de"
                "apellidos" => "Almeida"
              ]
              2 => array:2 [
                "nombre" => "Pedro Henrique Evangelista"
                "apellidos" => "Martinez"
              ]
              3 => array:2 [
                "nombre" => "Ana Let&#237;cia"
                "apellidos" => "Boff"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "pt"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S0365059622000435"
          "doi" => "10.1016/j.abd.2021.09.005"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622000435?idApp=UINPBA00008Z"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275222000595?idApp=UINPBA00008Z"
      "url" => "/26662752/0000009700000003/v1_202206050551/S2666275222000595/v1_202206050551/pt/main.assets"
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0365059622000393"
    "issn" => "03650596"
    "doi" => "10.1016/j.abd.2020.12.012"
    "estado" => "S300"
    "fechaPublicacion" => "2022-05-01"
    "aid" => "533"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by/4.0/"
    "subdocumento" => "sco"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Research Letter</span>"
      "titulo" => "Allergic contact dermatitis to corticosteroids&#58; experience of a referral clinic from 2014 to 2018"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "379"
          "paginaFinal" => "382"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 2164
              "Ancho" => 1340
              "Tamanyo" => 341943
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Eczema on the lower limb due to allergic contact dermatitis to corticosteroid&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Mariana de Figueiredo Silva Hafner, Amanda Ivanchuk Lopes, Nathalie Mie Suzuki, Rosana Lazzarini"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Mariana de Figueiredo Silva"
              "apellidos" => "Hafner"
            ]
            1 => array:2 [
              "nombre" => "Amanda Ivanchuk"
              "apellidos" => "Lopes"
            ]
            2 => array:2 [
              "nombre" => "Nathalie Mie"
              "apellidos" => "Suzuki"
            ]
            3 => array:2 [
              "nombre" => "Rosana"
              "apellidos" => "Lazzarini"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "pt" => array:9 [
        "pii" => "S2666275222000522"
        "doi" => "10.1016/j.abdp.2022.03.011"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "pt"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275222000522?idApp=UINPBA00008Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622000393?idApp=UINPBA00008Z"
    "url" => "/03650596/0000009700000003/v1_202205170747/S0365059622000393/v1_202205170747/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S0365059622000290"
    "issn" => "03650596"
    "doi" => "10.1016/j.abd.2021.04.015"
    "estado" => "S300"
    "fechaPublicacion" => "2022-05-01"
    "aid" => "523"
    "copyright" => "Sociedade Brasileira de Dermatologia"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by/4.0/"
    "subdocumento" => "crp"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Images in Dermatology</span>"
      "titulo" => "Isolated hair loss on the eyebrow&#58; five cases with trichoscopic features"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "372"
          "paginaFinal" => "375"
        ]
      ]
      "contieneResumen" => array:1 [
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0025"
          "etiqueta" => "Figure 5"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr5.jpeg"
              "Alto" => 606
              "Ancho" => 1304
              "Tamanyo" => 130786
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0025"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Broken hair &#40;red arrow&#41;&#44; comma hair &#40;red circle&#41;&#46; &#40;B&#41;&#44; Tulip hair &#40;green circle&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "G&#252;ldehan At&#305;&#351;, Ay&#351;enur &#350;am Sar&#305;, Pembeg&#252;l G&#252;ne&#351;, Cansu S&#246;nmez"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "G&#252;ldehan"
              "apellidos" => "At&#305;&#351;"
            ]
            1 => array:2 [
              "nombre" => "Ay&#351;enur &#350;am"
              "apellidos" => "Sar&#305;"
            ]
            2 => array:2 [
              "nombre" => "Pembeg&#252;l"
              "apellidos" => "G&#252;ne&#351;"
            ]
            3 => array:2 [
              "nombre" => "Cansu"
              "apellidos" => "S&#246;nmez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "pt" => array:9 [
        "pii" => "S266627522200042X"
        "doi" => "10.1016/j.abdp.2022.03.001"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "pt"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S266627522200042X?idApp=UINPBA00008Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622000290?idApp=UINPBA00008Z"
    "url" => "/03650596/0000009700000003/v1_202205170747/S0365059622000290/v1_202205170747/en/main.assets"
  ]
  "en" => array:19 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">What is your diagnosis&#63;</span>"
    "titulo" => "Case for diagnosis&#46; Radiotherapy-induced pemphigus vegetans"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "376"
        "paginaFinal" => "378"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Hiram Larangeira de Almeida Jr, Ant&#244;nia Larangeira de Almeida, Pedro Henrique Evangelista Martinez, Ana Let&#237;cia Boff"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "Hiram Larangeira de"
            "apellidos" => "Almeida Jr"
            "email" => array:1 [
              0 => "hiramalmeidajr@hotmail.com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Ant&#244;nia Larangeira de"
            "apellidos" => "Almeida"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Pedro Henrique Evangelista"
            "apellidos" => "Martinez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Ana Let&#237;cia"
            "apellidos" => "Boff"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "P&#243;s-Gradua&#231;&#227;o em Sa&#250;de e Comportamento&#44; Universidade Cat&#243;lica de Pelotas&#44; Departamento de Dermatologia&#44; Universidade Federal de Pelotas&#44; Pelotas&#44; RS&#44; Brazil"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Liga de Dermatologia&#44; Universidade Federal de Pelotas&#44; Pelotas&#44; RS&#44; Brazil"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Laborat&#243;rio Dermapat and Santa Casa de Miseric&#243;rdia de Porto Alegre&#44; Porto Alegre&#44; RS&#44; Brazil"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 611
            "Ancho" => 905
            "Tamanyo" => 70089
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Initial clinical aspect with perianal and intergluteal erosion with circinate pustular edges and some isolated pustules&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect1005">Case report</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 73-year-old male patient developed a vegetating lesion in the anal canal nine months ago&#59; the histopathology showed a non-keratinizing poorly differentiated squamous cell carcinoma&#46; He was treated with two cycles of 5-fluorouracil and cisplatin and concomitant radiotherapy &#40;6&#8201;MeV linear photon accelerator&#44; total dose of 54&#8201;Gy&#41;&#44; with complete remission&#46; The control colonoscopy and endoscopy after six months of treatment were normal&#46; Forty-five days before coming to the clinic again&#44; he had a painful perianal and intergluteal erosion with circinate pustular borders and some isolated pustules&#44; with surrounding erythema &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; He was hospitalized and received systemic antibiotics &#40;ceftriaxone and clindamycin&#41; and famciclovir&#46; A computed tomography on admission ruled out tumor recurrence&#44; showing a normal anal canal&#46; An incisional biopsy was performed&#44; which showed pseudoepitheliomatous hyperplasia with microabscesses of inflammatory cells &#40;neutrophils and eosinophils&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; In some microscopic fields&#44; clefts with isolated keratinocytes next to microabscesses were observed &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">What is your diagnosis&#63;</span><p id="par0010" class="elsevierStylePara elsevierViewall"><ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">a&#41;</span><p id="par0015" class="elsevierStylePara elsevierViewall">Ulcerated herpes simplex associated with immunosuppression</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">b&#41;</span><p id="par0020" class="elsevierStylePara elsevierViewall">Ulcerated radiodermatitis</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">c&#41;</span><p id="par0025" class="elsevierStylePara elsevierViewall">Pemphigus vegetans</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">d&#41;</span><p id="par0030" class="elsevierStylePara elsevierViewall">Tinea associated with immunosuppression</p></li></ul></p><p id="par0035" class="elsevierStylePara elsevierViewall">The histopathological findings were suggestive of pemphigus vegetans&#44; which may present with acantholytic clefts associated with polymorphonuclear microabscesses&#44;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> unlike classic pemphigus vulgaris in which the cleavage is accompanied by little inflammation&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">There was no therapeutic response to systemic antibiotics and antivirals initiated before the results of the investigation&#44; and there was significant regression with oral prednisone &#40;40&#8201;mg&#41; and topical betamethasone&#46; After seven days&#44; the pustular border disappeared&#44; and there was total symptom regression&#44; with the appearance of some hyperkeratotic and verrucous central areas &#40;<a class="elsevierStyleCrossRef" href="#fig0020">Fig&#46; 4</a>&#41;&#46; Later&#44; the result of indirect immunofluorescence was positive for IgG&#44; with an intercellular pattern&#44; 1&#58;80 titer&#46;</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">There are several reports of radiotherapy-induced pemphigus vulgaris&#44; but not of the vegetans variant&#46; Reported cases are restricted to the irradiated area&#44;<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2&#44;3</span></a> &#40;similarly to the case described here&#41; or generalized&#46;<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#44;5</span></a> There have also been reports of pemphigus foliaceus induction&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">The mechanism of induction of autoimmune acantholytic diseases by radiotherapy must be complex&#46; One possibility is the antigenic alteration by radiation&#59;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> another possibility would be the alteration of the immune response&#46; Corroborating the hypothesis of antigenic alteration&#44; there are reports of laboratory investigation with immunoblotting demonstrating antibodies against antigens other than desmogleins&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">This case demonstrates the possibility that pemphigus vegetans lesions may occur locally on a previously irradiated area&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect1015">Financial support</span><p id="par0060" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Authors&#8217; contributions</span><p id="par0065" class="elsevierStylePara elsevierViewall">Hiram Larangeira de Almeida Jr&#46;&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis&#44; and interpretation of data&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Ant&#244;nia Larangeira de Almeida&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis&#44; and interpretation of data&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Pedro Henrique Evangelista Martinez&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis&#44; and interpretation of data&#59; intellectual participation in propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Ana Let&#237;cia Boff&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis&#44; and interpretation of data&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conflicts of interest</span><p id="par0085" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:8 [
        0 => array:3 [
          "identificador" => "xres1711211"
          "titulo" => "Abstract"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0005"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec1513461"
          "titulo" => "Keywords"
        ]
        2 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Case report"
        ]
        3 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "What is your diagnosis&#63;"
        ]
        4 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Financial support"
        ]
        5 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Authors&#8217; contributions"
        ]
        6 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Conflicts of interest"
        ]
        7 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2021-07-16"
    "fechaAceptado" => "2021-09-13"
    "PalabrasClave" => array:1 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1513461"
          "palabras" => array:2 [
            0 => "Radiotherapy"
            1 => "Pemphigus vegetans"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:1 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar1030" class="elsevierStyleSimplePara elsevierViewall">A 73-year-old male patient developed a poorly differentiated squamous cell carcinoma in the anal canal nine months ago&#46; He was treated with two cycles of 5-fluorouracil and cisplatin and concomitant radiotherapy &#40;6&#8201;MeV linear photon accelerator&#44; total dose of 54&#8201;Gy&#41;&#44; with complete remission&#46; Since forty-five days he presentes a painful perianal and intergluteal erosion with circinate pustular borders&#46; Light microscopy showed pseudoepitheliomatous hyperplasia of the epidermis with microabscesses of inflammatory cells &#40;neutrophils and eosinophils&#41; and acantholytic keratinocytes &#46; Indirect immunofluorescence was positive for IgG&#44; with an intercellular pattern&#44; 1&#58;80 titer&#46; The diagnosis of radiotherapy-induced pemphigus vegetans was established and there was significant regression with oral prednisone &#40;40 mg&#41; and topical betamethasone&#46;</p></span>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Study conducted at the Liga de Dermatologia da Universidade Federal de Pelotas&#44; Pelotas&#44; RS&#44; Brazil&#46;</p>"
      ]
    ]
    "multimedia" => array:4 [
      0 => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 611
            "Ancho" => 905
            "Tamanyo" => 70089
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Initial clinical aspect with perianal and intergluteal erosion with circinate pustular edges and some isolated pustules&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1606
            "Ancho" => 1508
            "Tamanyo" => 721987
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0010"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Light microscopy showing clefts and polymorphonuclear microabscess &#40;Hematoxylin &#38; eosin&#44; &#215;150&#41;&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 788
            "Ancho" => 905
            "Tamanyo" => 251024
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0015"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Light microscopy detailing the clefts and polymorphonuclear microabscess with suprabasal cleavage &#40;arrows&#41; and acantholytic keratinocytes &#40;arrowheads&#41;&#59; &#40;Hematoxylin &#38; eosin&#44; &#215;400&#41;&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "fig0020"
        "etiqueta" => "Figure 4"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr4.jpeg"
            "Alto" => 669
            "Ancho" => 905
            "Tamanyo" => 117476
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0020"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Clinical aspect with significant improvement after seven days of treatment&#44; without the circinate pustular borders and mild verrucosity in the center&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:7 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pemphigus vegetans associated with verrucous lesions&#58; expanding a phenotype"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "H&#46;L&#46; Almeida Jr"
                            1 => "M&#46;G&#46;P&#46; Neugebauer"
                            2 => "I&#46;M&#46; Guarenti"
                            3 => "V&#46; Aoki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Clinics &#40;S&#227;o Paulo&#41;"
                        "fecha" => "2006"
                        "volumen" => "61"
                        "paginaInicial" => "279"
                        "paginaFinal" => "282"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#91;Radiotherapy-induced pemphigus&#93;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;P&#46; Correia"
                            1 => "D&#46; Santos"
                            2 => "M&#46; Jorge"
                            3 => "S&#46; Coutinho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Med Port"
                        "fecha" => "1998"
                        "volumen" => "11"
                        "paginaInicial" => "581"
                        "paginaFinal" => "583"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9773540"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiation-induced pemphigus vulgaris of the breast"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "R&#46; Vigna-Taglianti"
                            1 => "E&#46;G&#46; Russi"
                            2 => "N&#46; Denaro"
                            3 => "G&#46; Numico"
                            4 => "R&#46; Brizio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer&#47;Radioth&#233;r"
                        "fecha" => "2011"
                        "volumen" => "15"
                        "paginaInicial" => "334"
                        "paginaFinal" => "337"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#91;Radiotherapy-induced pemphigus&#58; a case report&#93;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Mseddi"
                            1 => "S&#46; Bouassida"
                            2 => "M&#46; Khemakhem"
                            3 => "S&#46; Marrekchi"
                            4 => "W&#46; Abdelmaksoud"
                            5 => "H&#46; Hadjtaieb"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.canrad.2004.10.007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer Radiother"
                        "fecha" => "2005"
                        "volumen" => "9"
                        "paginaInicial" => "96"
                        "paginaFinal" => "98"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15820437"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiation-associated pemphigus vulgaris in a patient with preceding malignancy&#58; treatment with rituximab as a valuable option"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "F&#46; Schauer"
                            1 => "N&#46; Ishii"
                            2 => "M&#46; Mockenhaupt"
                            3 => "L&#46; Bruckner-Tuderman"
                            4 => "T&#46; Hashimoto"
                            5 => "D&#46; Kiritsi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3389/fimmu.2019.03116"
                      "Revista" => array:5 [
                        "tituloSerie" => "Front Immunol"
                        "fecha" => "2020"
                        "volumen" => "10"
                        "paginaInicial" => "3116"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32038636"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiotherapy-induced Pemphigus Foliaceous&#58; a rare adverse effect of breast cancer therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "P&#46;R&#46; Criado"
                            1 => "C&#46;D&#46;A&#46; Machado Filho"
                            2 => "R&#46;F&#46;J&#46; Criado"
                            3 => "I&#46;C&#46;R&#46; Etcheverria"
                            4 => "L&#46;M&#46; Umeda"
                            5 => "G&#46; Landman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2018"
                        "volumen" => "57"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiotherapy-induced pemphigus vulgaris with autoantibodies targeting a 110 kDa epidermal antigen"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "T&#46; Badri"
                            1 => "H&#46; Hammami"
                            2 => "A&#46; Lachkham"
                            3 => "R&#46; Benmously-Mlika"
                            4 => "I&#46; Mokhtar"
                            5 => "S&#46; Fenniche"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-4632.2011.04889.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2011"
                        "volumen" => "50"
                        "paginaInicial" => "1475"
                        "paginaFinal" => "1479"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22097992"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/03650596/0000009700000003/v1_202205170747/S0365059622000435/v1_202205170747/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "80633"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "What is your Diagnosis&#63;"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03650596/0000009700000003/v1_202205170747/S0365059622000435/v1_202205170747/en/main.pdf?idApp=UINPBA00008Z&text.app=https://clinics.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059622000435?idApp=UINPBA00008Z"
]
Article information
ISSN: 03650596
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 27 5 32
2024 October 175 61 236
2024 September 234 76 310
2024 August 234 109 343
2024 July 156 101 257
2024 June 131 75 206
2024 May 127 61 188
2024 April 110 96 206
2024 March 101 68 169
2024 February 121 96 217
2024 January 108 64 172
2023 December 74 55 129
2023 November 75 92 167
2023 October 62 67 129
2023 September 76 68 144
2023 August 48 33 81
2023 July 53 32 85
2023 June 65 43 108
2023 May 50 25 75
2023 April 37 18 55
2023 March 67 50 117
2023 February 54 40 94
2023 January 31 39 70
2022 December 56 30 86
2022 November 87 53 140
2022 October 82 50 132
2022 September 64 67 131
2022 August 42 48 90
2022 July 55 58 113
2022 June 89 72 161
2022 May 105 97 202
2022 April 43 52 95
2022 March 29 44 73
Show all

Follow this link to access the full text of the article

Idiomas
Anais Brasileiros de Dermatologia
en pt
Cookies policy Política de cookies
To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.