array:23 [
  "pii" => "S0365059621001549"
  "issn" => "03650596"
  "doi" => "10.1016/j.abd.2021.03.004"
  "estado" => "S300"
  "fechaPublicacion" => "2021-09-01"
  "aid" => "397"
  "copyright" => "Sociedade Brasileira de Dermatologia"
  "copyrightAnyo" => "2021"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by/4.0/"
  "subdocumento" => "crp"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S0365059621001677"
    "issn" => "03650596"
    "doi" => "10.1016/j.abd.2020.08.024"
    "estado" => "S300"
    "fechaPublicacion" => "2021-09-01"
    "aid" => "410"
    "copyright" => "Sociedade Brasileira de Dermatologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by/4.0/"
    "subdocumento" => "sco"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Research Letter</span>"
      "titulo" => "Clinical and epidemiological profile of mycetoma patients from a tertiary care center in Karachi&#44; Pakistan"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "617"
          "paginaFinal" => "619"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1075
              "Ancho" => 1508
              "Tamanyo" => 593407
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Histopathology showing two different types of colonies &#40;Hematoxylin &#38; eosin&#44; &#215;10&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Yousuf Abd Mallick, Nausheen Yaqoob"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Yousuf Abd"
              "apellidos" => "Mallick"
            ]
            1 => array:2 [
              "nombre" => "Nausheen"
              "apellidos" => "Yaqoob"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "pt" => array:9 [
        "pii" => "S2666275221001958"
        "doi" => "10.1016/j.abdp.2021.07.018"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "pt"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275221001958?idApp=UINPBA00008Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059621001677?idApp=UINPBA00008Z"
    "url" => "/03650596/0000009600000005/v4_202110020832/S0365059621001677/v4_202110020832/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S0365059621001781"
    "issn" => "03650596"
    "doi" => "10.1016/j.abd.2020.10.009"
    "estado" => "S300"
    "fechaPublicacion" => "2021-09-01"
    "aid" => "421"
    "copyright" => "Sociedade Brasileira de Dermatologia"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by/4.0/"
    "subdocumento" => "crp"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Images in Dermatology</span>"
      "titulo" => "Bowen&#8217;s disease of the penile shaft presenting as a pigmented macule&#58; dermoscopy&#44; reflectance confocal microscopy and histopathological correlation"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "609"
          "paginaFinal" => "612"
        ]
      ]
      "contieneResumen" => array:1 [
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0015"
          "etiqueta" => "Figure 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 1495
              "Ancho" => 1505
              "Tamanyo" => 569284
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0015"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Histopathology showing in the epidermis atypical features consisting of abnormal maturation of keratinocytes&#44; prominent nucleoli&#44; and many dyskeratotic cells &#40;arrows&#41;&#46; In the superficial dermis&#44; ectatic vessels&#44; a moderate lymphohistiocytic infiltrate and melanophages may be observed &#40;Hematoxyline &#38; eosin&#44; &#215;150&#41;&#46; &#40;B&#41;&#44; At immunohistochemistry CD1a&#160;&#43;&#160;Langerhans cells&#44; may be observed &#40;Immunohistochemical&#44; &#215;200&#41;&#46; &#40;C&#41;&#44; Immunohistochemical staining for Melan A showed no atypical melanocytes&#46; Hyperpigmentation of keratinocytes of the basal layer is evident &#40;Immunohistochemical&#44; &#215;150&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Francesco Lacarrubba, Anna Elisa Verz&#236;, Rosario Caltabiano, Giuseppe Micali"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Francesco"
              "apellidos" => "Lacarrubba"
            ]
            1 => array:2 [
              "nombre" => "Anna Elisa"
              "apellidos" => "Verz&#236;"
            ]
            2 => array:2 [
              "nombre" => "Rosario"
              "apellidos" => "Caltabiano"
            ]
            3 => array:2 [
              "nombre" => "Giuseppe"
              "apellidos" => "Micali"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "pt" => array:9 [
        "pii" => "S2666275221002083"
        "doi" => "10.1016/j.abdp.2021.07.029"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "pt"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275221002083?idApp=UINPBA00008Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059621001781?idApp=UINPBA00008Z"
    "url" => "/03650596/0000009600000005/v4_202110020832/S0365059621001781/v4_202110020832/en/main.assets"
  ]
  "en" => array:19 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">What is your diagnosis&#63;</span>"
    "titulo" => "Case for diagnosis&#46; Ulcer and papular lesions in a patient with diabetes mellitus&#46; Protothecosis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "613"
        "paginaFinal" => "616"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Larissa Daniele Machado G&#243;es, Vin&#237;cius da Silva Monteiro, Ana Tereza Orsi de Souza"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "Larissa Daniele Machado"
            "apellidos" => "G&#243;es"
            "email" => array:1 [
              0 => "larissadaniele55@gmail.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Vin&#237;cius da Silva"
            "apellidos" => "Monteiro"
          ]
          2 => array:2 [
            "nombre" => "Ana Tereza Orsi de"
            "apellidos" => "Souza"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Funda&#231;&#227;o de Dermatologia Tropical e Venereologia Alfredo da Matta&#44; Manaus&#44; AM&#44; Brazil"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 972
            "Ancho" => 1505
            "Tamanyo" => 299240
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0015"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Sporangia highlighted in black with silver staining &#40;Grocott&#44; &#215;400&#41;&#59; &#40;B&#41;&#44; Sporangia highlighted by PAS staining &#40;PAS&#44; &#215;400&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Case report</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 79-year-old woman&#44; born and living in the municipality of Manaus&#44; with non-insulin-dependent diabetes mellitus&#44; with a pacemaker&#44; was referred with a histopathological diagnosis of cryptococcosis&#44; and reporting a two-year evolution of the disease&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The dermatological examination showed an ulcer on the right scapula and erythematous-papular lesions&#44; isolated and confluent&#44; forming small plaques&#44; located on the left scapula &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A and B&#41;&#46; Serologies were negative for HIV&#44; syphilis&#44; hepatitis B and C&#46; Histopathological examination showed a granulomatous dermal infiltrate and rounded structures&#44; isolated or grouped&#44; of different sizes&#44; inside histiocytes and giant cells &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>A and B&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">What is your diagnosis&#63;</span><p id="par0015" class="elsevierStylePara elsevierViewall"><ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">a&#41;</span><p id="par0020" class="elsevierStylePara elsevierViewall">Cutaneous leishmaniasis</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">b&#41;</span><p id="par0025" class="elsevierStylePara elsevierViewall">Prothotecosis</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">c&#41;</span><p id="par0030" class="elsevierStylePara elsevierViewall">Cryptococcosis</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">d&#41;</span><p id="par0035" class="elsevierStylePara elsevierViewall">Paracoccidioidomycosis</p></li></ul></p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Discussion</span><p id="par0040" class="elsevierStylePara elsevierViewall">PAS and Grocott staining showed rounded structures and endosporulation with a morula aspect &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>A and B&#41;&#46; Analysis of the molecular structure of material obtained from culture showed the presence of <span class="elsevierStyleItalic">Prototheca wickerhamii</span>&#46; This histopathological and molecular biology data exclude the hypotheses of cryptococcosis&#44; leishmaniasis and paracoccidioidomycosis&#46; The final diagnosis was protothecosis&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">Protothecosis is an opportunistic disease caused by achlorophilic algae of the genus <span class="elsevierStyleItalic">Prototheca</span>&#44; found in dogs&#44; bats&#44; in fresh and saltwater&#44; sewage&#44; soil&#44; and cattle milk&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a> Humans are accidentally contaminated through skin scratches&#44; inhalation&#44; or ingestion of the etiological agent&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Human protothecosis is rare and occurs&#44; in most cases&#44; in immunocompromised patients&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> In general&#44; the clinical manifestations are predominantly cutaneous&#46; Bursitis and systemic involvement have also been reported&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5&#44;6</span></a> The main agents of protothecosis are <span class="elsevierStyleItalic">Prototheca zopfii</span> and <span class="elsevierStyleItalic">P&#46; wickerhamii</span>&#44; with the latter being the most common&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> Infiltrated plaques and ulcerated lesions are the most frequent clinical presentations&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> Papular&#44; nodular&#44; pustular&#44; vesicular and verrucous lesions can occur&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Clinically&#44; all the suggested diagnostic possibilities should be considered&#46; The hypothesis of leishmaniasis is relevant&#44; as the patient lives in Manaus &#40;Brazil&#41; and this disease has been diagnosed with relative frequency in patients with no history of having left the city&#46; Residual areas of primary and&#47;or secondary forests are the main reservoirs of the disease in the urban area&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Paracoccidioidomycosis can cause similar clinical manifestations&#44; but the patient had no history of activity in rural areas&#46; This diagnosis and the hypothesis of cutaneous cryptococcosis were also ruled out through laboratory tests&#46; The patient had no complaints or clinical evidence of systemic disease associated with protothecosis&#46; The image exams &#40;chest radiography and computed tomography&#41; were normal&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">The patient was treated with 200&#160;mg&#47;day of itraconazole&#46; There was almost total regression of the lesions&#59; however&#44; the patient died due to complications from COVID-19&#46; Itraconazole has been used for varying periods from 14 to 180 days&#46;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7&#44;8</span></a> Amphotericin B is recommended for immunosuppressed patients&#46;<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">9&#44;10</span></a></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Financial support</span><p id="par0060" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Authors&#8217; contributions</span><p id="par0065" class="elsevierStylePara elsevierViewall">Larissa Daniele Machado G&#243;es&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis and interpretation of data&#59; effective participation in research orientation&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Vin&#237;cius da Silva Monteiro&#58; Design and planning of the study&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Ana Tereza Orsi de Souza&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis and interpretation of data&#59; effective participation in research orientation&#59; intellectual participation in propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conflicts of interest</span><p id="par0080" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:9 [
        0 => array:3 [
          "identificador" => "xres1581942"
          "titulo" => "Abstract"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0005"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec1423935"
          "titulo" => "Keywords"
        ]
        2 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Case report"
        ]
        3 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "What is your diagnosis&#63;"
        ]
        4 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Discussion"
        ]
        5 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Financial support"
        ]
        6 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Authors&#8217; contributions"
        ]
        7 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Conflicts of interest"
        ]
        8 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2021-01-15"
    "fechaAceptado" => "2021-03-30"
    "PalabrasClave" => array:1 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1423935"
          "palabras" => array:3 [
            0 => "Infectious dermatoses"
            1 => "Opportunistic infections"
            2 => "Prototheca"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:1 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Protothecosis is a rare disease caused by achlorophilic algae of the genus <span class="elsevierStyleItalic">Prototheca spp</span>&#46; In general&#44; three clinical forms are observed&#58; cutaneous&#44; articular and systemic&#46; The cutaneous form is the most common one&#46; This study describes a patient with isolated erythematous papules and erythematous papular plaques in the scapular regions&#44; with a previous histopathological diagnosis of cryptococcosis&#46; New tests were conclusive for the diagnosis of protothecosis&#44; caused by <span class="elsevierStyleItalic">Prototheca wickerhamii</span>&#46;</p></span>"
      ]
    ]
    "NotaPie" => array:2 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">How to cite this article&#58; G&#243;es LDM&#44; Monteiro VS&#44; Souza ATO&#46; Case for Diagnosis&#46; Ulcer and papular lesions in a patient with diabetes mellitus&#46; Protothecosis&#46; An Bras Dermatol&#46; 2021&#59;96&#58;613&#8211;6&#46;</p>"
      ]
      1 => array:2 [
        "etiqueta" => "&#9734;&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0010">Study conducted at the Funda&#231;&#227;o de Dermatologia Tropical e Venereologia Alfredo da Matta&#44; Manaus&#44; AM&#44; Brazil&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 930
            "Ancho" => 1500
            "Tamanyo" => 187900
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Ulcerated lesion&#44; with raised edges and an erythematous and hemorrhagic fundus&#46; Purpuric lesions secondary to trauma&#59; &#40;B&#41;&#44; Erythematous papular plaques on the scapula&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 966
            "Ancho" => 1505
            "Tamanyo" => 338778
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0010"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Granulomatous dermal infiltrate consisting of lymphocytes&#44; histiocytes&#44; multinucleated giant cells and rounded structures&#44; isolated or grouped&#44; of different sizes&#44; inside histiocytes and giant cells &#40;Hematoxylin &#38; eosin&#44; &#215;100&#41;&#59; &#40;B&#41;&#44; Greater detail of sporangia&#44; hematoxylin-eosin staining &#40;Hematoxylin &#38; eosin&#44; &#215;400&#41;&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 972
            "Ancho" => 1505
            "Tamanyo" => 299240
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0015"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Sporangia highlighted in black with silver staining &#40;Grocott&#44; &#215;400&#41;&#59; &#40;B&#41;&#44; Sporangia highlighted by PAS staining &#40;PAS&#44; &#215;400&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:10 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sustained Presence of Cutaneous Leishmaniasis in Urban Manaus&#44; the Largest Human Settlement in the Amazon"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Ben&#237;cio"
                            1 => "M&#46; Cordeiro"
                            2 => "H&#46; Monteiro"
                            3 => "M&#46;A&#46;S&#46; Moura"
                            4 => "C&#46; Oliveira"
                            5 => "E&#46;P&#46;N&#46; Gadelha"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4269/ajtmh.14-0164"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Trop Med Hyg"
                        "fecha" => "2015"
                        "volumen" => "93"
                        "paginaInicial" => "1208"
                        "paginaFinal" => "1213"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26483119"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous protothecosis--case report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "P&#46;C&#46; Silva"
                            1 => "S&#46;B&#46; Costa e Silva"
                            2 => "R&#46;B&#46; Lima"
                            3 => "A&#46;M&#46; D&#8217;Acri"
                            4 => "O&#46; Lupi"
                            5 => "C&#46;J&#46; Martins"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1590/abd1806-4841.20132232"
                      "Revista" => array:7 [
                        "tituloSerie" => "An Bras Dermatol"
                        "fecha" => "2013"
                        "volumen" => "88"
                        "numero" => "6 Supl 1"
                        "paginaInicial" => "183"
                        "paginaFinal" => "185"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24346914"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous protothecosis in patient with diabetes mellitus and review of published case reports"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "Q&#46;Q&#46; Zhang"
                            1 => "L&#46; Li"
                            2 => "L&#46;P&#46; Zhu"
                            3 => "Y&#46; Zhao"
                            4 => "Y&#46;R&#46; Wang"
                            5 => "J&#46;H&#46; Zhu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11046-011-9480-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mycopathologia"
                        "fecha" => "2012"
                        "volumen" => "173"
                        "paginaInicial" => "163"
                        "paginaFinal" => "171"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21964624"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prototheca wickerhamii hand infection successfully treated by itraconazole and voriconazole"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Sheikh-Ahmad"
                            1 => "S&#46; Goldstein"
                            2 => "I&#46; Potasman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1708-8305.2006.00062.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Travel Med"
                        "fecha" => "2006"
                        "volumen" => "13"
                        "paginaInicial" => "321"
                        "paginaFinal" => "323"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16987132"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Human protothecosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Lass-Fl&#246;rl"
                            1 => "A&#46; Mayr"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1128/CMR.00032-06"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Microbiol Rev"
                        "fecha" => "2007"
                        "volumen" => "20"
                        "paginaInicial" => "230"
                        "paginaFinal" => "242"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17428884"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous protothecosis in kidney transplant recipient"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "V&#46;R&#46; Godofredo"
                            1 => "M&#46;M&#46;S&#46;E&#46;S&#46; Enokihara"
                            2 => "J&#46; Tomimori"
                            3 => "M&#46;M&#46; Ogawa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.abd.2019.08.022"
                      "Revista" => array:6 [
                        "tituloSerie" => "An Bras Dermatol"
                        "fecha" => "2020"
                        "volumen" => "95"
                        "paginaInicial" => "210"
                        "paginaFinal" => "213"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32059817"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Protothecosis in patients with cancer&#58; case series and literature review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "H&#46;A&#46; Torres"
                            1 => "G&#46;P&#46; Bodey"
                            2 => "J&#46;J&#46; Tarrand"
                            3 => "D&#46;P&#46; Kontoyiannis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1469-0691.2003.00600.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Microbiol Infect"
                        "fecha" => "2003"
                        "volumen" => "9"
                        "paginaInicial" => "786"
                        "paginaFinal" => "792"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14616698"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinicopathological features and course of cutaneous protothecosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "H&#46;C&#46; Tseng"
                            1 => "C&#46;B&#46; Chen"
                            2 => "J&#46;C&#46; Ho"
                            3 => "Y&#46;W&#46; Cheng"
                            4 => "H&#46;W&#46; Huang"
                            5 => "P&#46;L&#46; Sun"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jdv.14804"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol"
                        "fecha" => "2018"
                        "volumen" => "32"
                        "paginaInicial" => "1575"
                        "paginaFinal" => "1583"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29356140"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Medical phycology 2017"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;R&#46; Todd"
                            1 => "T&#46; Matsumoto"
                            2 => "R&#46; Ueno"
                            3 => "J&#46; Murugaiyan"
                            4 => "A&#46; Britten"
                            5 => "J&#46;W&#46; King"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/mmy/myx162"
                      "Revista" => array:7 [
                        "tituloSerie" => "Med Mycol"
                        "fecha" => "2018"
                        "volumen" => "56"
                        "numero" => "suppl&#95;1"
                        "paginaInicial" => "S188"
                        "paginaFinal" => "S204"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29767780"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Emergence of Fungal-Like Organisms&#58; Prototheca"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Kano"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11046-019-00365-4"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mycopathologia"
                        "fecha" => "2020"
                        "volumen" => "185"
                        "paginaInicial" => "747"
                        "paginaFinal" => "754"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31401758"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/03650596/0000009600000005/v4_202110020832/S0365059621001549/v4_202110020832/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "80633"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "What is your Diagnosis&#63;"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03650596/0000009600000005/v4_202110020832/S0365059621001549/v4_202110020832/en/main.pdf?idApp=UINPBA00008Z&text.app=https://clinics.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059621001549?idApp=UINPBA00008Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

What is your diagnosis?
Case for diagnosis. Ulcer and papular lesions in a patient with diabetes mellitus. Protothecosis
Larissa Daniele Machado Góes
Corresponding author
larissadaniele55@gmail.com

Corresponding author.
, Vinícius da Silva Monteiro, Ana Tereza Orsi de Souza
Fundação de Dermatologia Tropical e Venereologia Alfredo da Matta, Manaus, AM, Brazil
Read
5504
Times
was read the article
2475
Total PDF
3029
Total HTML
Share statistics
 array:23 [
  "pii" => "S0365059621001549"
  "issn" => "03650596"
  "doi" => "10.1016/j.abd.2021.03.004"
  "estado" => "S300"
  "fechaPublicacion" => "2021-09-01"
  "aid" => "397"
  "copyright" => "Sociedade Brasileira de Dermatologia"
  "copyrightAnyo" => "2021"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by/4.0/"
  "subdocumento" => "crp"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S0365059621001677"
    "issn" => "03650596"
    "doi" => "10.1016/j.abd.2020.08.024"
    "estado" => "S300"
    "fechaPublicacion" => "2021-09-01"
    "aid" => "410"
    "copyright" => "Sociedade Brasileira de Dermatologia"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by/4.0/"
    "subdocumento" => "sco"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Research Letter</span>"
      "titulo" => "Clinical and epidemiological profile of mycetoma patients from a tertiary care center in Karachi&#44; Pakistan"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "617"
          "paginaFinal" => "619"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1075
              "Ancho" => 1508
              "Tamanyo" => 593407
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Histopathology showing two different types of colonies &#40;Hematoxylin &#38; eosin&#44; &#215;10&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Yousuf Abd Mallick, Nausheen Yaqoob"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Yousuf Abd"
              "apellidos" => "Mallick"
            ]
            1 => array:2 [
              "nombre" => "Nausheen"
              "apellidos" => "Yaqoob"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "pt" => array:9 [
        "pii" => "S2666275221001958"
        "doi" => "10.1016/j.abdp.2021.07.018"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "pt"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275221001958?idApp=UINPBA00008Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059621001677?idApp=UINPBA00008Z"
    "url" => "/03650596/0000009600000005/v4_202110020832/S0365059621001677/v4_202110020832/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S0365059621001781"
    "issn" => "03650596"
    "doi" => "10.1016/j.abd.2020.10.009"
    "estado" => "S300"
    "fechaPublicacion" => "2021-09-01"
    "aid" => "421"
    "copyright" => "Sociedade Brasileira de Dermatologia"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by/4.0/"
    "subdocumento" => "crp"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Images in Dermatology</span>"
      "titulo" => "Bowen&#8217;s disease of the penile shaft presenting as a pigmented macule&#58; dermoscopy&#44; reflectance confocal microscopy and histopathological correlation"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "609"
          "paginaFinal" => "612"
        ]
      ]
      "contieneResumen" => array:1 [
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0015"
          "etiqueta" => "Figure 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 1495
              "Ancho" => 1505
              "Tamanyo" => 569284
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0015"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Histopathology showing in the epidermis atypical features consisting of abnormal maturation of keratinocytes&#44; prominent nucleoli&#44; and many dyskeratotic cells &#40;arrows&#41;&#46; In the superficial dermis&#44; ectatic vessels&#44; a moderate lymphohistiocytic infiltrate and melanophages may be observed &#40;Hematoxyline &#38; eosin&#44; &#215;150&#41;&#46; &#40;B&#41;&#44; At immunohistochemistry CD1a&#160;&#43;&#160;Langerhans cells&#44; may be observed &#40;Immunohistochemical&#44; &#215;200&#41;&#46; &#40;C&#41;&#44; Immunohistochemical staining for Melan A showed no atypical melanocytes&#46; Hyperpigmentation of keratinocytes of the basal layer is evident &#40;Immunohistochemical&#44; &#215;150&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Francesco Lacarrubba, Anna Elisa Verz&#236;, Rosario Caltabiano, Giuseppe Micali"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Francesco"
              "apellidos" => "Lacarrubba"
            ]
            1 => array:2 [
              "nombre" => "Anna Elisa"
              "apellidos" => "Verz&#236;"
            ]
            2 => array:2 [
              "nombre" => "Rosario"
              "apellidos" => "Caltabiano"
            ]
            3 => array:2 [
              "nombre" => "Giuseppe"
              "apellidos" => "Micali"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "pt" => array:9 [
        "pii" => "S2666275221002083"
        "doi" => "10.1016/j.abdp.2021.07.029"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "pt"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2666275221002083?idApp=UINPBA00008Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059621001781?idApp=UINPBA00008Z"
    "url" => "/03650596/0000009600000005/v4_202110020832/S0365059621001781/v4_202110020832/en/main.assets"
  ]
  "en" => array:19 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">What is your diagnosis&#63;</span>"
    "titulo" => "Case for diagnosis&#46; Ulcer and papular lesions in a patient with diabetes mellitus&#46; Protothecosis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "613"
        "paginaFinal" => "616"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Larissa Daniele Machado G&#243;es, Vin&#237;cius da Silva Monteiro, Ana Tereza Orsi de Souza"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "Larissa Daniele Machado"
            "apellidos" => "G&#243;es"
            "email" => array:1 [
              0 => "larissadaniele55@gmail.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Vin&#237;cius da Silva"
            "apellidos" => "Monteiro"
          ]
          2 => array:2 [
            "nombre" => "Ana Tereza Orsi de"
            "apellidos" => "Souza"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Funda&#231;&#227;o de Dermatologia Tropical e Venereologia Alfredo da Matta&#44; Manaus&#44; AM&#44; Brazil"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 972
            "Ancho" => 1505
            "Tamanyo" => 299240
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0015"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Sporangia highlighted in black with silver staining &#40;Grocott&#44; &#215;400&#41;&#59; &#40;B&#41;&#44; Sporangia highlighted by PAS staining &#40;PAS&#44; &#215;400&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Case report</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 79-year-old woman&#44; born and living in the municipality of Manaus&#44; with non-insulin-dependent diabetes mellitus&#44; with a pacemaker&#44; was referred with a histopathological diagnosis of cryptococcosis&#44; and reporting a two-year evolution of the disease&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The dermatological examination showed an ulcer on the right scapula and erythematous-papular lesions&#44; isolated and confluent&#44; forming small plaques&#44; located on the left scapula &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A and B&#41;&#46; Serologies were negative for HIV&#44; syphilis&#44; hepatitis B and C&#46; Histopathological examination showed a granulomatous dermal infiltrate and rounded structures&#44; isolated or grouped&#44; of different sizes&#44; inside histiocytes and giant cells &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>A and B&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">What is your diagnosis&#63;</span><p id="par0015" class="elsevierStylePara elsevierViewall"><ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">a&#41;</span><p id="par0020" class="elsevierStylePara elsevierViewall">Cutaneous leishmaniasis</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">b&#41;</span><p id="par0025" class="elsevierStylePara elsevierViewall">Prothotecosis</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">c&#41;</span><p id="par0030" class="elsevierStylePara elsevierViewall">Cryptococcosis</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">d&#41;</span><p id="par0035" class="elsevierStylePara elsevierViewall">Paracoccidioidomycosis</p></li></ul></p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Discussion</span><p id="par0040" class="elsevierStylePara elsevierViewall">PAS and Grocott staining showed rounded structures and endosporulation with a morula aspect &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>A and B&#41;&#46; Analysis of the molecular structure of material obtained from culture showed the presence of <span class="elsevierStyleItalic">Prototheca wickerhamii</span>&#46; This histopathological and molecular biology data exclude the hypotheses of cryptococcosis&#44; leishmaniasis and paracoccidioidomycosis&#46; The final diagnosis was protothecosis&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">Protothecosis is an opportunistic disease caused by achlorophilic algae of the genus <span class="elsevierStyleItalic">Prototheca</span>&#44; found in dogs&#44; bats&#44; in fresh and saltwater&#44; sewage&#44; soil&#44; and cattle milk&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a> Humans are accidentally contaminated through skin scratches&#44; inhalation&#44; or ingestion of the etiological agent&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Human protothecosis is rare and occurs&#44; in most cases&#44; in immunocompromised patients&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> In general&#44; the clinical manifestations are predominantly cutaneous&#46; Bursitis and systemic involvement have also been reported&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5&#44;6</span></a> The main agents of protothecosis are <span class="elsevierStyleItalic">Prototheca zopfii</span> and <span class="elsevierStyleItalic">P&#46; wickerhamii</span>&#44; with the latter being the most common&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> Infiltrated plaques and ulcerated lesions are the most frequent clinical presentations&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> Papular&#44; nodular&#44; pustular&#44; vesicular and verrucous lesions can occur&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Clinically&#44; all the suggested diagnostic possibilities should be considered&#46; The hypothesis of leishmaniasis is relevant&#44; as the patient lives in Manaus &#40;Brazil&#41; and this disease has been diagnosed with relative frequency in patients with no history of having left the city&#46; Residual areas of primary and&#47;or secondary forests are the main reservoirs of the disease in the urban area&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Paracoccidioidomycosis can cause similar clinical manifestations&#44; but the patient had no history of activity in rural areas&#46; This diagnosis and the hypothesis of cutaneous cryptococcosis were also ruled out through laboratory tests&#46; The patient had no complaints or clinical evidence of systemic disease associated with protothecosis&#46; The image exams &#40;chest radiography and computed tomography&#41; were normal&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">The patient was treated with 200&#160;mg&#47;day of itraconazole&#46; There was almost total regression of the lesions&#59; however&#44; the patient died due to complications from COVID-19&#46; Itraconazole has been used for varying periods from 14 to 180 days&#46;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7&#44;8</span></a> Amphotericin B is recommended for immunosuppressed patients&#46;<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">9&#44;10</span></a></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Financial support</span><p id="par0060" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Authors&#8217; contributions</span><p id="par0065" class="elsevierStylePara elsevierViewall">Larissa Daniele Machado G&#243;es&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis and interpretation of data&#59; effective participation in research orientation&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Vin&#237;cius da Silva Monteiro&#58; Design and planning of the study&#59; intellectual participation in the propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Ana Tereza Orsi de Souza&#58; Approval of the final version of the manuscript&#59; design and planning of the study&#59; drafting and editing of the manuscript&#59; collection&#44; analysis and interpretation of data&#59; effective participation in research orientation&#59; intellectual participation in propaedeutic and&#47;or therapeutic conduct of the studied cases&#59; critical review of the literature&#59; critical review of the manuscript&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conflicts of interest</span><p id="par0080" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:9 [
        0 => array:3 [
          "identificador" => "xres1581942"
          "titulo" => "Abstract"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0005"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec1423935"
          "titulo" => "Keywords"
        ]
        2 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Case report"
        ]
        3 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "What is your diagnosis&#63;"
        ]
        4 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Discussion"
        ]
        5 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Financial support"
        ]
        6 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Authors&#8217; contributions"
        ]
        7 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Conflicts of interest"
        ]
        8 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2021-01-15"
    "fechaAceptado" => "2021-03-30"
    "PalabrasClave" => array:1 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1423935"
          "palabras" => array:3 [
            0 => "Infectious dermatoses"
            1 => "Opportunistic infections"
            2 => "Prototheca"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:1 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Protothecosis is a rare disease caused by achlorophilic algae of the genus <span class="elsevierStyleItalic">Prototheca spp</span>&#46; In general&#44; three clinical forms are observed&#58; cutaneous&#44; articular and systemic&#46; The cutaneous form is the most common one&#46; This study describes a patient with isolated erythematous papules and erythematous papular plaques in the scapular regions&#44; with a previous histopathological diagnosis of cryptococcosis&#46; New tests were conclusive for the diagnosis of protothecosis&#44; caused by <span class="elsevierStyleItalic">Prototheca wickerhamii</span>&#46;</p></span>"
      ]
    ]
    "NotaPie" => array:2 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">How to cite this article&#58; G&#243;es LDM&#44; Monteiro VS&#44; Souza ATO&#46; Case for Diagnosis&#46; Ulcer and papular lesions in a patient with diabetes mellitus&#46; Protothecosis&#46; An Bras Dermatol&#46; 2021&#59;96&#58;613&#8211;6&#46;</p>"
      ]
      1 => array:2 [
        "etiqueta" => "&#9734;&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0010">Study conducted at the Funda&#231;&#227;o de Dermatologia Tropical e Venereologia Alfredo da Matta&#44; Manaus&#44; AM&#44; Brazil&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 930
            "Ancho" => 1500
            "Tamanyo" => 187900
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Ulcerated lesion&#44; with raised edges and an erythematous and hemorrhagic fundus&#46; Purpuric lesions secondary to trauma&#59; &#40;B&#41;&#44; Erythematous papular plaques on the scapula&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 966
            "Ancho" => 1505
            "Tamanyo" => 338778
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0010"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Granulomatous dermal infiltrate consisting of lymphocytes&#44; histiocytes&#44; multinucleated giant cells and rounded structures&#44; isolated or grouped&#44; of different sizes&#44; inside histiocytes and giant cells &#40;Hematoxylin &#38; eosin&#44; &#215;100&#41;&#59; &#40;B&#41;&#44; Greater detail of sporangia&#44; hematoxylin-eosin staining &#40;Hematoxylin &#38; eosin&#44; &#215;400&#41;&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 972
            "Ancho" => 1505
            "Tamanyo" => 299240
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0015"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41;&#44; Sporangia highlighted in black with silver staining &#40;Grocott&#44; &#215;400&#41;&#59; &#40;B&#41;&#44; Sporangia highlighted by PAS staining &#40;PAS&#44; &#215;400&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:10 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sustained Presence of Cutaneous Leishmaniasis in Urban Manaus&#44; the Largest Human Settlement in the Amazon"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Ben&#237;cio"
                            1 => "M&#46; Cordeiro"
                            2 => "H&#46; Monteiro"
                            3 => "M&#46;A&#46;S&#46; Moura"
                            4 => "C&#46; Oliveira"
                            5 => "E&#46;P&#46;N&#46; Gadelha"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4269/ajtmh.14-0164"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Trop Med Hyg"
                        "fecha" => "2015"
                        "volumen" => "93"
                        "paginaInicial" => "1208"
                        "paginaFinal" => "1213"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26483119"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous protothecosis--case report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "P&#46;C&#46; Silva"
                            1 => "S&#46;B&#46; Costa e Silva"
                            2 => "R&#46;B&#46; Lima"
                            3 => "A&#46;M&#46; D&#8217;Acri"
                            4 => "O&#46; Lupi"
                            5 => "C&#46;J&#46; Martins"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1590/abd1806-4841.20132232"
                      "Revista" => array:7 [
                        "tituloSerie" => "An Bras Dermatol"
                        "fecha" => "2013"
                        "volumen" => "88"
                        "numero" => "6 Supl 1"
                        "paginaInicial" => "183"
                        "paginaFinal" => "185"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24346914"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous protothecosis in patient with diabetes mellitus and review of published case reports"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "Q&#46;Q&#46; Zhang"
                            1 => "L&#46; Li"
                            2 => "L&#46;P&#46; Zhu"
                            3 => "Y&#46; Zhao"
                            4 => "Y&#46;R&#46; Wang"
                            5 => "J&#46;H&#46; Zhu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11046-011-9480-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mycopathologia"
                        "fecha" => "2012"
                        "volumen" => "173"
                        "paginaInicial" => "163"
                        "paginaFinal" => "171"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21964624"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prototheca wickerhamii hand infection successfully treated by itraconazole and voriconazole"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Sheikh-Ahmad"
                            1 => "S&#46; Goldstein"
                            2 => "I&#46; Potasman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1708-8305.2006.00062.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Travel Med"
                        "fecha" => "2006"
                        "volumen" => "13"
                        "paginaInicial" => "321"
                        "paginaFinal" => "323"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16987132"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Human protothecosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Lass-Fl&#246;rl"
                            1 => "A&#46; Mayr"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1128/CMR.00032-06"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Microbiol Rev"
                        "fecha" => "2007"
                        "volumen" => "20"
                        "paginaInicial" => "230"
                        "paginaFinal" => "242"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17428884"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous protothecosis in kidney transplant recipient"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "V&#46;R&#46; Godofredo"
                            1 => "M&#46;M&#46;S&#46;E&#46;S&#46; Enokihara"
                            2 => "J&#46; Tomimori"
                            3 => "M&#46;M&#46; Ogawa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.abd.2019.08.022"
                      "Revista" => array:6 [
                        "tituloSerie" => "An Bras Dermatol"
                        "fecha" => "2020"
                        "volumen" => "95"
                        "paginaInicial" => "210"
                        "paginaFinal" => "213"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32059817"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Protothecosis in patients with cancer&#58; case series and literature review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "H&#46;A&#46; Torres"
                            1 => "G&#46;P&#46; Bodey"
                            2 => "J&#46;J&#46; Tarrand"
                            3 => "D&#46;P&#46; Kontoyiannis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1469-0691.2003.00600.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Microbiol Infect"
                        "fecha" => "2003"
                        "volumen" => "9"
                        "paginaInicial" => "786"
                        "paginaFinal" => "792"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14616698"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinicopathological features and course of cutaneous protothecosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "H&#46;C&#46; Tseng"
                            1 => "C&#46;B&#46; Chen"
                            2 => "J&#46;C&#46; Ho"
                            3 => "Y&#46;W&#46; Cheng"
                            4 => "H&#46;W&#46; Huang"
                            5 => "P&#46;L&#46; Sun"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jdv.14804"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol"
                        "fecha" => "2018"
                        "volumen" => "32"
                        "paginaInicial" => "1575"
                        "paginaFinal" => "1583"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29356140"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Medical phycology 2017"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;R&#46; Todd"
                            1 => "T&#46; Matsumoto"
                            2 => "R&#46; Ueno"
                            3 => "J&#46; Murugaiyan"
                            4 => "A&#46; Britten"
                            5 => "J&#46;W&#46; King"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/mmy/myx162"
                      "Revista" => array:7 [
                        "tituloSerie" => "Med Mycol"
                        "fecha" => "2018"
                        "volumen" => "56"
                        "numero" => "suppl&#95;1"
                        "paginaInicial" => "S188"
                        "paginaFinal" => "S204"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29767780"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Emergence of Fungal-Like Organisms&#58; Prototheca"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Kano"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11046-019-00365-4"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mycopathologia"
                        "fecha" => "2020"
                        "volumen" => "185"
                        "paginaInicial" => "747"
                        "paginaFinal" => "754"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31401758"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/03650596/0000009600000005/v4_202110020832/S0365059621001549/v4_202110020832/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "80633"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "What is your Diagnosis&#63;"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03650596/0000009600000005/v4_202110020832/S0365059621001549/v4_202110020832/en/main.pdf?idApp=UINPBA00008Z&text.app=https://clinics.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365059621001549?idApp=UINPBA00008Z"
]
Article information
ISSN: 03650596
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 14 6 20
2024 October 113 74 187
2024 September 144 71 215
2024 August 148 122 270
2024 July 147 103 250
2024 June 119 94 213
2024 May 95 65 160
2024 April 107 83 190
2024 March 119 83 202
2024 February 96 75 171
2024 January 87 51 138
2023 December 56 61 117
2023 November 66 79 145
2023 October 60 75 135
2023 September 92 92 184
2023 August 67 25 92
2023 July 98 43 141
2023 June 65 47 112
2023 May 57 24 81
2023 April 40 20 60
2023 March 56 43 99
2023 February 57 42 99
2023 January 47 37 84
2022 December 53 39 92
2022 November 75 57 132
2022 October 72 66 138
2022 September 56 71 127
2022 August 45 50 95
2022 July 45 62 107
2022 June 60 60 120
2022 May 35 49 84
2022 April 63 47 110
2022 March 64 62 126
2022 February 50 33 83
2022 January 72 109 181
2021 December 65 61 126
2021 November 76 59 135
2021 October 97 83 180
2021 September 102 85 187
2021 August 32 45 77
2021 July 17 22 39
Show all

Follow this link to access the full text of the article

Idiomas
Anais Brasileiros de Dermatologia
en pt
Cookies policy Política de cookies
To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.